Publications by authors named "Gelza Mae A Zabat"
Background: ABO1020 is a monovalent COVID-19 mRNA vaccine. Results from a phase 1 trial showed ABO1020 was safe and well tolerated, and phase 3 trials to evaluate the efficacy, immunogenicity, and safety of ABO1020 in healthy adults are urgently needed.
Methods: We conducted a multinational, randomized, placebo-controlled, double-blind, phase 3 trial among healthy adults (ClinicalTrials.
Article Synopsis
- The Panbio COVID-19/Flu A&B Panel is a rapid diagnostic test that detects SARS-CoV-2 and influenza A and B proteins from nasal swab samples taken from symptomatic individuals.
- This study is the largest of its kind, involving over 1,600 participants across multiple continents to evaluate the test's sensitivity and specificity compared to a standard assay using nasopharyngeal swabs.
- The results showed that the Panbio test has high sensitivity (around 80-94%) and specificity (over 99%) for detecting COVID-19 and influenza, making it a reliable option for quick diagnosis in various populations.
Background: The live-attenuated influenza virus vector-based intranasal SARS-CoV-2 vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing, China) confers long-lasting and broad protection in animal models and is, to our knowledge, the first COVID-19 mucosal vaccine to enter into human trials, but its efficacy is still unknown. We aimed to assess the safety and efficacy (but not the immunogenicity) of dNS1-RBD against COVID-19.
Methods: We did a multicentre, randomised, double-blind, placebo-controlled, adaptive design, phase 3 trial at 33 centres (private or public hospitals, clinical research centres, or Centre for Disease Control and Prevention) in four countries (Colombia, Philippines, South Africa, and Viet Nam).
An electronic medical record system can help scale up the HIV/AIDS treatment program of a country. The authors illustrate how an HIV/AIDS electronic medical record system (HIV/AIDS EMR) was designed and implemented among treatment facilities across the Philippines.
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