Publications by authors named "Geltrude Giura"
Background: Oral anticoagulation therapy is frequently prescribed to kidney transplant recipients (KTRs) for prevention and treatment of thrombotic events. Over the past 10 y, direct oral anticoagulants (DOACs) have shown similar efficacy with a safety profile equal or superior to that of vitamin K antagonist anticoagulants (VKAs) in the general population. However, little data are available on kidney transplantation.
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- A study analyzed the management of hypertrophic cardiomyopathy (HCM) in 1431 patients across 26 French medical centers, revealing differences between expert and non-expert facilities.
- Patients at non-expert centers were typically older and more likely to experience severe symptoms, while also having fewer genetic confirmations of their condition compared to those treated at expert sites.
- The findings highlight significant disparities in diagnostic and treatment approaches for HCM, suggesting that non-sarcomeric forms of the disease may be underrecognized and improperly managed outside of specialized centers.
The assessment of left ventricular shape changes during cardiac revolution may be a new step in clinical cardiology to ease early diagnosis and treatment. To quantify these changes, only point registration was adopted and neither Generalized Procrustes Analysis nor Principal Component Analysis were applied as we did previously to study a group of healthy subjects. Here, we extend to patients affected by hypertrophic cardiomyopathy the original approach and preliminarily include genotype positive/phenotype negative individuals to explore the potential that incumbent pathology might also be detected.
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