[Endoprosthesis of the elbow joint in sequelae of gunshot wounds].

5 patients have been implanted the endoprostheses of Sivash K. M. to restore functions of the upper limb after the gunshot injury in the area of elbow joint with the clinico-roentgenologic bone defect detection.

Ethanol-diazepam interactions on delayed match-to-sample performance in baboons.

Four juvenile male baboons were trained on a delayed match-to-sample (MTS) discrimination task. Single administration of 0.25, 0.

Ethanol and chronic diazepam interactions on conflict behavior in rats.

Four groups of five rats each received training on the Geller-Seifter procedure and then received 0.5, 1.0 or 2.

[Rehabilitative treatment in endoprosthesis of the elbow joint].

A technique of rehabilitation treatment was suggested and tested on 25 patients with an elbow joint endoprosthesis. The postoperative rehabilitation involved three periods: absolute immobilization, relative immobilization and postimmobilization. Therapeutic measures should be adjusted to each specific stage and imply different physiotherapeutic modalities according to clinical features and duration of the postoperative period: position treatment; passive, light active dynamic exercise, isometric training, underwater exercise; electrostimulation; manual and mechanical massage; occupational therapy.

[Educational level as a factor in length of life].

"The paper deals with...

Interactive effects of diazepam and ethanol on baboon match-to-sample performance.

Four juvenile male baboons were trained to perform a match-to-sample (MTS) discrimination task. Diazepam (DZ) at doses of 0.5, 1.

Ethanol and diazepam interactions on conflict behavior in rats.

Twenty-four adult male rats trained on the Geller-Seifter conflict procedure received: 1.0, 2.0, or 4.

Effects of subchronic soman on avoidance-escape behavior and cholinesterase activities.

Male Sprague-Dawley rats were trained on a discriminated avoidance-escape task. They were administered subchronically saline, 12.7 micrograms/kg (0.

Neurobehavioral effects of repeated sublethal soman in primates.

Juvenile male baboons were trained to perform a match-to-sample discrimination task; effects of repeated sublethal exposure to the organophosphate nerve gas, soman, upon task performance were then explored. Both acute and subchronic exposure schedules were employed, and soman potency was verified by assay of soman-induced inhibition of acetylcholinesterase activity in whole blood, plasma, and erythrocytes. A characteristic profile of behavioral effects encompassing immediate, persistent, and delayed effects was observed.

Effects of subchronic administration of soman on acquisition of avoidance-escape behavior by laboratory rats.

Holtzman male Sprague-Dawley rats were given four injections of saline or soman at 31 micrograms/kg or 46 micrograms/kg. The injections were given every 3 days during a 2-week period. Tail vein blood samples, drawn 24 hr before the first injection and 24 hr after the last injection, were analyzed for acetylcholinesterase (AChE) inhibition.

Acute soman effects in the juvenile baboon: effects on a match-to-sample discrimination task and on total blood acetylcholinesterase.

Male juvenile baboons, trained on a match-to-sample operant discrimination task, were given acute intramuscular injections of soman (methyl pinacolyl phosphonofluoridate) at 1.0, 2.0, 3.

Toluene and ethanol effects on baboon match-to-sample performance: possible synergistic action.

Four juvenile male baboons were trained to respond for banana pellet rewards on a match-to-sample discrimination task. Exposure of the animals to a range of concentrations of either toluene or ethanol vapor resulted in a slowing of response times and a reduction in the percent trials attempted for some concentrations of either vapor. When behaviorally ineffective (subthreshold) concentrations of each vapor were combined, effects upon response times and trials attempted were similar to the effects produced by the higher concentrations of the individual vapors.

Exploratory studies of a rodent model for inhalant abuse.

For simulation of inhalant abuse exposure conditions, male and female rats were exposed to high concentrations (10,000-30,000 ppm) toluene vapor until unconscious (8-12 min periods). Sex differences were observed in the mean times to onset of sleep during exposure; linear regression lines of min to sleep onset as a function of toluene/kg body wt had slopes of -0.7492 for males and -0.

Behavioral effects of drugs as a function of maternal polybrominated biphenyl body burden.

Prior to breeding, female rats were dosed orally for 20 days with either 0.5 mg/kg polybrominated biphenyl (PBB), 5.0 mg/kg PBB, or the lecithin liposome vehicle.

Effect of exposure to high concentrations of toluene on ethanol preference of laboratory rats.

Male and female Holtzman Sprague Dawley rats were given 10-minute exposures to high concentrations of toluene twice a week at 10-30 days of age. The rate of acquisition of ethanol preference for these rats did not differ significantly from litter-mate sham exposed controls. Once ethanol preference curves were established, the rats were exposed daily over a 5-day period to high concentrations of toluene.

Toluene inhalation and anxiolytic activity: possible synergism with diazepam.

Toluene exposures or injections of diazepam reinstated lever responses that had been suppressed by punishment in laboratory rats. When concentrations of toluene or diazepam that were ineffective or minimally effective in this paradigm were administered in combination, they produced a qualitatively similar effect which was much greater than the sum total of effects produced by the same amount of either substance alone. These observations suggest an anxiolytic action for toluene and a possible synergism between the two substances.

Phenobarbital and d-amphetamine effects on discrimination performance of rats and juvenile baboons.

Hungry rats in Skinner boxes were trained to select the right or left lever as correct as a function of the presence of a tone or light stimulus, respectively. Correct responses produced liquid food rewards. Acute intraperitoneal administration of d-amphetamine or phenobarbital did not affect accuracy of performance, but decreased the percent trials attempted and lengthened response times as a function of increasing doses.