Publications by authors named "Gelin Zhang"
Chondrocyte ferroptosis plays a crucial role in osteoarthritis (OA) progression. Our previous study demonstrated that TRIM8 knockdown alleviated IL-1β-induced chondrocyte injury. However, the involvement of TRIM8 in regulating OA progression through ferroptosis remains unclear.
View Article and Find Full Text PDFModulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression.
J Cardiovasc Transl Res
June 2024
Recent research shows exercise is good for heart health, emphasizing the importance of physical activity. Sedentary behavior increases the risk of cardiovascular disease, while exercise can help prevent and treat it. Additionally, physical exercise can modulate the expression of lncRNAs, influencing cardiovascular disease progression.
View Article and Find Full Text PDFBackground: The goat cervical spine represents a promising alternative for human specimen in spinal implant testing, but the range of motion (ROM) of the spine is lacking. We aimed to evaluate and compare the ROMs of fresh goat and human mid-cervical spine specimens.
Methods: Ten fresh adult healthy male goat cervical spine specimens (G group) and ten fresh frozen adult healthy human cervical spine specimens (average age: 49.
[Detection of HPV 58 and cloning of its E7 gene in cervical cancer].
Zhonghua Zhong Liu Za Zhi
September 2004
Article Synopsis
- The study aimed to detect HPV 58 in cervical cancer biopsy specimens and to clone its E7 gene for potential diagnostic and vaccine development.
- Researchers used PCR and fluorescent detection methods on 58 biopsy samples, finding that 10 were HPV 58-positive, which is about 19.2% of the HPV-positive cases.
- The E7 gene was successfully amplified, cloned, and expressed in bacteria, suggesting that HPV 58 is prevalent among women with cervical cancer in Shaanxi province and that the recombinant plasmids can be useful for future research.