[Geographical distribution of MTHFR and MTRR gene polymorphisms among the Han women in Zhengzhou city].

Objective: To explore the genotype distribution of 5,10-methylenetetrahydrofolate reductase (MTHFR) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) among Chinese Han women in Zhengzhou. 


Methods: A total of 1 253 women were recruited from Zhengzhou city. The genotype of MTHFR C677T, A1298C and MTRR A66G was detected to analyze the distribution of gene polymorphisms and to compare them with the published data from other Han women.

Discrepancy in impact of maternal milk on vertical transmission between Hepatitis B virus and Human cytomegalovirus.

Objectives: This study aims to elucidate the role of breastfeeding on vertical transmission of HCMV and HBV and to investigate the difference in perinatal transmission via breast milk between HBV and HCMV.

Methods: This detailed study monitored the kinetics of viral DNA load in maternal milk for both HBV and HCMV, demonstrated the rate of transmission to infants, and compared HBV infection rate with that of HCMV.

Results: There was no difference in overall DNAlactia+ between HBV (23.