Publications by authors named "Gehad E Elkhouly"

Hepatocellular carcinoma (HCC) ranks as the third leading cause of cancer-related deaths worldwide. Current treatment strategies include surgical resection, liver transplantation, liver-directed therapy, and systemic therapy. Sorafenib (Sor) is the first systemic drug authorized by the US Food and Drug Administration (FDA) for HCC treatment.

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Article Synopsis
  • Hand hygiene is critical for preventing infections, with alcohol-based sanitizers widely used but causing skin issues during the COVID-19 pandemic.
  • Rhamnolipids nano-micelles are shown to have comparable antibacterial effects and lower toxicity than alcohol sanitizers, with promising antiviral activity against SARS-CoV-2 without harming human cells.
  • The nano-micelles demonstrated no irritation in animal testing and could be a safer alternative for hand sanitation, although further testing in healthcare settings is required.
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Hospital-acquired infections (HAIs) are considered to be a major global healthcare challenge, in large part because of the development of microbial resistance to currently approved antimicrobial drugs. HAIs are frequently preventable through infection prevention and control measures, with hand hygiene as a key activity. Improving hand hygiene was reported to reduce the transmission of healthcare-associated pathogens and HAIs.

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COVID-19 is a pandemic disease caused by the SARS-CoV-2, which continues to cause global health and economic problems since emerging in China in late 2019. Until now, there are no standard antiviral treatments. Thus, several strategies were adopted to minimize virus transmission, such as social distancing, face covering protection and hand hygiene.

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