Symptoms and Central Sensory Integration in People With Chronic mTBI: Clinical Implications.

Introduction: Balance deficits in people with chronic mild traumatic brain injury (mTBI; ≥3 months post-mTBI), thought to relate to central sensory integration deficits, are subtle and often difficult to detect. The purpose of this study was to determine the sensitivity of the instrumented modified clinical test of sensory integration for balance (mCTSIB) in identifying such balance deficits in people with symptomatic, chronic mTBI and to establish the associations between balance and mTBI symptom scores in the chronic mTBI group.

Methods: The Institutional Review Board approved these study methods.

Use of Wearable Sensors to Assess the Effects of Performing a Cognitive Task on Sensory Integration of Balance in Healthy Individuals.

This study investigated the effects of performing a cognitive task on the sensory integration of balance in healthy individuals. Ten subjects (five F/five M; 21.5 ± 2.

Gait and Balance Changes with Investigational Peripheral Nerve Cell Therapy during Deep Brain Stimulation in People with Parkinson's Disease.

Background: The efficacy of deep brain stimulation (DBS) and dopaminergic therapy is known to decrease over time. Hence, a new investigational approach combines implanting autologous injury-activated peripheral nerve grafts (APNG) at the time of bilateral DBS surgery to the globus pallidus interna.

Objectives: In a study where APNG was unilaterally implanted into the substantia nigra, we explored the effects on clinical gait and balance assessments over two years in 14 individuals with Parkinson's disease.

Cerebellar White Matter Damage Is Associated With Postural Sway Deficits in People With Multiple Sclerosis.

Objective: To assess how postural sway deficits during eyes open and closed relate to the integrity of cerebellar peduncles in individuals with multiple sclerosis (MS).

Design: Cross-sectional study.

Setting: Laboratory based setting.

Inertial Sensor-Based Assessment of Central Sensory Integration for Balance After Mild Traumatic Brain Injury.

Introduction: Optimal balance control requires a complex integration of sensory information from the visual, vestibular, and proprioceptive systems. The goal of this study is to determine if the instrumented modified Clinical Test of Sensory Integration and Balance (mCTSIB) was impaired acutely after mild traumatic brain injury (mTBI) when postural sway under varying sensory conditions was measured with a wearable inertial sensor.

Materials And Methods: Postural sway was assessed in athletes who had sustained a mTBI within the past 2-3 d (n = 38) and control athletes (n = 81).

Validity of the Instrumented Push and Release Test to Quantify Postural Responses in Persons With Multiple Sclerosis.

Objective: To test the validity of wearable inertial sensors to provide objective measures of postural stepping responses to the push and release clinical test in people with multiple sclerosis.

Design: Cross-sectional study.

Setting: University medical center balance disorder laboratory.

Corpus Callosum Structural Integrity Is Associated With Postural Control Improvement in Persons With Multiple Sclerosis Who Have Minimal Disability.

Background: Improvement of postural control in persons with multiple sclerosis (PwMS) is an important target for neurorehabilitation. Although PwMS are able to improve postural performance with training, the neural underpinnings of these improvements are poorly understood.

Objective: To understand the neural underpinnings of postural motor learning in PwMS.

Instrumented Test of Sensory Integration for Balance: A Validation Study.

Background And Purpose: Abnormal postural sway is associated with an increase in risk of falls but is difficult for clinicians to accurately quantify without access to laboratory equipment. Instrumenting clinical outcome measures using body-worn movement monitors is a low-cost alternative. This is the first study to compare the modified Clinical Test of Sensory Integration for Balance (i-mCTSIB) to the laboratory test of the Sensory Organization Test (SOT) with dynamic posturography in a group of participants with Parkinson's disease (PD) and subtle balance limitations.

Trunk Muscle Coordination During Upward and Downward Reaching in Stroke Survivors.

In this study, we investigated deficits in coordination of trunk muscle modes involved in the stabilization of the trunk's trajectory for reaching upward and downward beyond functional arm length. Trunk muscle activity from 10 stroke survivors (8 men, 2 women; 64.1 ± 10.

Postural Motor Learning Deficits in People With MS in Spatial but Not Temporal Control of Center of Mass.

Background: Multiple sclerosis (MS) is associated with balance deficits resulting in falls and impaired mobility. Although rehabilitation has been recommended to address these balance deficits, the extent to which people with MS can learn and retain improvements in postural responses is unknown.

Aim: To determine the ability of people with MS to improve postural control with surface perturbation training.

Relationship of diminished interjoint coordination after stroke to hand path consistency.

Differences between 12 left-brain (LCVA, 65.4 ± 11.7 years old) and 10 right-brain (RCVA, 61 ± 12.

Trunk Muscle Coordination During Upward and Downward Reaching in Stroke Survivors.

In this study, we investigated deficits in coordination of trunk muscle modes involved in the stabilization of the trunk's trajectory for reaching upward and downward beyond functional arm length. Trunk muscle activity from 10 stroke survivors (8 men, 2 women; 64.1 ± 10.

Timing variability of reach trajectories in left versus right hemisphere stroke.

This study investigated trajectory timing variability in right and left stroke survivors and healthy controls when reaching to a centrally located target under a fixed target condition or when the target could suddenly change position after reach onset. Trajectory timing variability was investigated with a novel method based on dynamic programming that identifies the steps required to time warp one trial's acceleration time series to match that of a reference trial. Greater trajectory timing variability of both hand and joint motions was found for the paretic arm of stroke survivors compared to their non-paretic arm or either arm of controls.

Motor abundance contributes to resolving multiple kinematic task constraints.

This study investigated the use of motor abundance during the transport and placing of objects that required either precise or minimal orientation to the target. Analyses across repetitions of the structure of joint configuration variance relative to the position and orientation constraints were performed using the Uncontrolled Manifold (UCM) approach. Results indicated that the orientation constraint did not affect stability of the hand's spatial path.