2-Pyrazolines as Biologically Active and Fluorescent Agents, An Overview.

Nitrogen-containing five-membered heterocyclics play a vital role in pharmaceuticals as well as medicinal chemistry. Pyrazolines play a significant role among other heterocycles because of their therapeutic and pharmacological properties. 2-Pyrazolines displayed a wide variety of biological activities such as anticancer, antiepileptic, anti-aids, antimalarial, insecticidal, antitubercular, etc.

Solvatochromic and single crystal studies of 3-(4-bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbaldehyde.

The structure of 3-(4-bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbaldehyde was determined by using X-ray diffraction analysis. Photophysical studies of the title compound were investigated in the solvents with different polarities. The emission spectrum of the compound was recorded in polar solvent DMSO (356 nm).

High-performance liquid chromatography analysis of plant saponins: An update 2005-2010.

Saponins are widely distributed in plant kingdom. In view of their wide range of biological activities and occurrence as complex mixtures, saponins have been purified and separated by high-performance liquid chromatography using reverse-phase columns at lower wavelength. Mostly, saponins are not detected by ultraviolet detector due to lack of chromophores.

RP-HPLC analysis and antidiabetic activity of Swertia paniculata.

1,2,6,8-Tetrahydroxyxanthone (SR1) and 2,8-dihydroxy-1,6-dimethoxyxanthone (SR2) have been qualitatively and quantitatively determined in leaves and rhizomes of Swertia paniculata. The methanol extracts were analyzed on a C18 column using MeOH and H20 as mobile phase at a flow rate of 1 mL/min. Identification was achieved using an UV variable lambda detector set at 260 nm.