Measured immunoglobulin E in allergic bronchopulmonary aspergillosis treated with omalizumab.

Background: The ability to assess adequate reductions in immunoglobulin E (IgE) in allergic bronchopulmonary aspergillosis (ABPA) has been a concern with regards to omalizumab treatment.

Objective: To describe the clinical course and serial measured IgE levels in two adult patients with elevated IgE levels, hypersensitivity to Aspergillus fumigatus, and bilateral bronchiectasis who were treated with omalizumab. CLINICAL DESCRIPTIONS: Patient 1 met commonly used criteria for ABPA and had a more than 3-fold increase (from 702 to 2462 IU/ml) in measured IgE 4 months after starting omalizumab.

Clinical associations of delirium in hospitalized adult patients and the role of on admission presentation.

Objective: To describe clinical associations of delirium in hospitalized patients and relationships to on admission presentation.

Design: Retrospective analysis of an administrative hospitalization database 1998-2007.

Setting: Acute care hospitalizations in the New York State (NYS).

Omalizumab-associated anaphylactic reactions reported between January 2007 and June 2008.

Background: Anaphylaxis associated with omalizumab treatment is a growing concern. The broader context in which omalizumab-associated allergic reactions occur has not been well described.

Objective: To identify and characterize recently reported anaphylactic reactions associated with omalizumab administration.

Clinical outcomes of endoscopic and endoscopic-assisted resection of inverted papillomas: a 15-year experience.

Background: The endoscopic resection of sinonasal inverted papillomas (IPs) has been well described. However, the majority of published reports in the literature are small case series with limited clinical follow-up. The aim of this retrospective study was to review the experience with the endoscopic and endoscopic-assisted resection of IPs at a major academic tertiary care facility and assess long-term outcomes.