Antimicrobial susceptibility patterns of urinary tract infections causing bacterial isolates and associated risk factors among HIV patients in Tigray, Northern Ethiopia.

Background: Urinary tract infections, a prevalent global infectious disease, are clinical issues not well studied in HIV-positive individuals. UTIs have become a global drug resistance issue, but the prevalence and antibiotic susceptibility patterns of UTI-causing bacteria among HIV patients in Tigray, Ethiopia, are poorly understood. This study aims to identify the prevalence of UTI-causing bacteria, their antibiotic susceptibility patterns, and associated risk factors in HIV patients attending ART clinics at Mekelle General Hospital and Ayder Comprehensive Specialized Hospital in Tigray, Northern Ethiopia.

Prevalence and Antimicrobial Resistance of Species and Associated Factors Among Under-Five Children with Diarrhea at Randomly Selected Public Health Facilities in Mekelle, Tigray, Ethiopia.

Background: species are the most predominant bacterial agents to cause diarrhea in under-five children. It poses a serious challenge to public health worldwide with ongoing acquisition of resistance to different antimicrobials with multiple patterns. Thus, this study aimed to determine the prevalence, and antimicrobial resistance of species, and associated factors among under-five children with diarrhea in selected public health facilities.

Biofilm-Inhibitory Activity of Wild Mushroom Extracts against Pathogenic Bacteria.

Objective: This study aims to investigate the bacterial biofilm-inhibitory effect of mushroom extracts.

Methods: Mushrooms were collected from Arabuko-Sokoke and Kakamega forests and identified using morphological and molecular approaches. , , , , and were extracted by chloroform, 70% ethanol, and hot water.

Phytochemical Constituents of L. (Baobab) Fruit Pulp from Tekeze Valley, Tigrai, Ethiopia.

Baobab ( L) is a large tree species growing in semiarid and arid lowlands of Ethiopia and other places. The plant is valued by natives for its contributions as a cash crop and livelihood tree. Previous studies using samples from different countries have documented their phytochemical profiles and nutritional and health benefits.

Wild Mushrooms: Potential Natural Sources of Antioxidant and Anti-Quorum Sensing Bioactive Compounds for Medical Applications.

Objective: This study was aimed at determining the antioxidant, anti-quorum sensing, and cytotoxic activities of five wild mushroom extracts.

Methods: Wild mushrooms of , , , and were collected from Arabuko-Sokoke and Kakamega National Forests, in Kenya. Specimens were identified and extracted using chloroform (CHL), 70% ethanol (Eth), and hot water (HW) solvents.

Wild Mushrooms: A Hidden Treasure of Novel Bioactive Compounds.

Secondary metabolites are hidden gems in mushrooms. Understanding these secondary metabolites' biological and pharmacological effects can be aided by identifying them. The purpose of this work was to profile the mycochemical components of the extracts of , , , , and to comprehend their biological and pharmacological capabilities.

Challenges of intervention, treatment, and antibiotic resistance of biofilm-forming microorganisms.

Background: Biofilms are multicellular communities of microorganisms held together by a self-produced extracellular matrix. The ability of microbes to form biofilm is a universal, ubiquitous, and dynamic process. This dynamic process of biofilms establishes an important strategy to withstand and survive harsh environmental conditions and antimicrobial agents.

Investigation of Antioxidant and Antimicrobial Activities of Different Extracts of and Species of Mushrooms.

Mushrooms produce a variety of bioactive compounds that are known to have a potential source of antioxidant and antimicrobial properties. Natural antioxidants can protect against free radicals without any side effects. The purpose of this study was to evaluate the antioxidant and antimicrobial activities of and extracts.

Determination of Antimicrobial Activity of Extracts of Indigenous Wild Mushrooms against Pathogenic Organisms.

Objective: This study has investigated the antimicrobial activity of extracts of indigenous wild mushrooms against selected organisms.

Methods: Thirty-five (35) indigenous wild mushrooms were collected from Arabuko-Sokoke and Kakamega National Reserve Forests, Kenya. All mushrooms were identified and their contents were extracted and screened for their antimicrobial activities against (clinical isolate) (ATCC 13883), (clinical isolate), (ATCC 27853), (ATCC 25923), MRSA (ATCC 33591), (clinical isolate), and (ATCC 90018) using tetrazolium microtiter plate bioassay method.

Isolation and characterization of potential antibiotic producing actinomycetes from water and sediments of Lake Tana, Ethiopia.

Objective: To isolate, evaluate and characterize potential antibiotic producing actinomycetes from water and sediments of Lake Tana, Ethiopia.

Methods: A total of 31 strains of actinomycetes were isolated and tested against Gram positive and Gram negative bacterial strains by primary screening. In the primary screening, 11 promising isolates were identified and subjected to solid state and submerged state fermentation methods to produce crude extracts.