Survival analysis of early initiation of antenatal care visits and associated factors among pregnant women in Ethiopia.

Introduction: Early initiation of antenatal care visits creates an opportunity for early detection of high-risk pregnancies, pregnancy complications, health education, and counseling about successful care and nutrition of the mother and the fetus. Thus, the main objective of this study was to identify the factors associated with the early initiation of antenatal care visits in Ethiopia.

Methods: The study was conducted based on the children's data set of the 2019 Ethiopia mini-demographic and health survey.

Genetic characterization of cashmere goat () populations in Mongolia.

Objective: Characterization studies of the phenotypic and genetic diversity of Mongolian goats are limited, despite several goat breeds being registered in the country. This study aimed to evaluate the phenotypic and genetic diversity of 14 cashmere goat populations in Mongolia, consisting largely of identified goat breeds.

Methods: Body weight, cashmere quality, and coat color were the phenotypic traits considered in this study.

Application of joint modeling on the determinants of TB Status and CD4 cell count among antiretroviral therapy attendants in Gondar teaching referral hospital, Gonder, Ethiopia.

Background: East African regions were highly affected by tuberculosis and the human immunodeficiency virus. The main objective was to identifying the associated factors with tuberculosis and CD4 cell count of patients in Gonder teaching referral hospital, Gonder, Ethiopia.

Methods: A retrospective cohort study was conducted on AIDS patients from 1 January 2018 - to 30 January 2020.

Genome-wide association study for milking speed in Fleckvieh cattle.

Milking speed is an important trait influencing the udder health of dairy cows, as well as labor efficiency. However, it has received little attention in genomic association studies. The main objective of this study was to determine regions and genes on the genome with a potential effect on milking speed in Fleckvieh (dual-purpose Simmental) cattle.

Incomplete Kawasaki disease presenting with a cellulitis-like plaque: Lessons from an unusual presentation.

Kawasaki disease (KD) is an acute small to medium-vessel vasculitis that primarily affects children under the age of 5 years. The cause of KD is unknown, but it is hypothesized to be a systemic inflammatory illness triggered by infections in genetically predisposed individuals. Diagnosis of incomplete KD is made in patients with prolonged fever without a source who do not meet diagnostic criteria but have some findings consistent with KD such as elevated inflammatory markers, transaminitis, and echocardiographic findings.

Bone marrow fibrosis is associated with non-response to CD19 CAR T-cell therapy in B-acute lymphoblastic leukemia.

CD19 directed CAR T-cell therapy is used to treat relapsed/refractory B-cell acute lymphoblastic leukemia. The role of the pre-CAR bone marrow (BM) stromal microenvironment in determining response to CAR T-cell therapy has been understudied. We performed whole transcriptome analysis, reticulin fibrosis assessment and CD3 T-cell infiltration on BM core biopsies from pre- and post-CAR timepoints for 61 patients, as well as on a cohort of 54 primary B-ALL samples.

Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Patients with Dermatomyositis with Refractory Skin Disease: A Randomized Clinical Trial.

Background: Treatment options are limited for skin disease in dermatomyositis. Lenabasum is a cannabinoid receptor type 2 agonist that triggers the resolution of inflammation.

Objective: The objective of this study was to evaluate the safety and efficacy of lenabasum in patients with refractory cutaneous dermatomyositis.

Haematology laboratory parameters to assess efficacy of CD19-, CD22-, CD33-, and CD123-directed chimeric antigen receptor T-cell therapy in haematological malignancies.

Introduction: Chimeric antigen receptor (CAR) T cell products are available to treat relapsed/refractory B-lymphoblastic leukaemia/lymphoma (B-ALL), diffuse large B-cell lymphoma, mantle-cell lymphoma, and myeloma. CAR products vary by their target epitope and constituent molecules. Hence, there are no common laboratory assays to assess CAR T cell expansion in the clinical setting.

Peer doula support training for Black and Indigenous groups in Nova Scotia, Canada: A community-based qualitative study.

Objectives: The objectives of this qualitative study were to explore participant experiences of doula training programs offered by a prisoner health advocacy organization and Indigenous and Black community groups.

Design: This investigation employed a qualitative design. Recruitment was conducted through email.

WITHDRAWN:Optimization and evaluation of alternative village-based breeding plans: the case of goats in Afar region, Ethiopia.

Ahead of Print article withdrawn by publisher.

Participatory definition of trait preferences and breeding practices of goats in Aba'ala, Afar region: as input for designing genetic improvement program.

A farmer participatory approach was used to identify trait preferences and breeding practices for Afar goat population in Aba'ala district, Afar region, Ethiopia. A rapid field survey followed by purposive sampling was used to identify research sites and 90 households representing agro-pastoral and pastoral production systems were selected purposively. Data were obtained from individual interview, own-flock ranking experiment, and secondary sources.

System dynamics modeling in designing breeding schemes: The case of Menz sheep in Ethiopian highlands.

A comprehensive dynamic simulation model was developed to describe a community-based breeding program for the Menz sheep population of Ethiopia. Selection of male and female animals based on their own and maternal performance was simulated. The breeding goal traits were 6-mo weight, preweaning survival, and fertility rate.

Polymerization-induced thermal self-assembly (PITSA).

Polymerization-induced self-assembly (PISA) is a versatile technique to achieve a wide range of polymeric nanoparticle morphologies. Most previous examples of self-assembled soft nanoparticle synthesis by PISA rely on a growing solvophobic polymer block that leads to changes in nanoparticle architecture during polymerization in a selective solvent. However, synthesis of block copolymers with a growing stimuli-responsive block to form various nanoparticle shapes has yet to be reported.