Systematic characterization of zinc in a series of breast cancer cell lines reveals significant changes in zinc homeostasis.

An optimal amount of labile zinc (Zn ) is essential for proliferation of human cells, where Zn levels that are too high or too low cause cell cycle exit. Tumors of the breast have been characterized by high levels of total Zn . Given the role of Zn in proliferation of human cells and elevation of zinc in breast cancer tumors, we examined the concentration of total and labile Zn across a panel of 5 breast cancer cell lines, compared to the normal MCF10A cell line.

Exploring timing and delivery of lifestyle advice following an acute cardiac event hospitalization: The cardiac patient's perspective.

Objective: To explore the perspective of cardiac patients regarding the timing and manner of delivering lifestyle advice following an acute cardiac event hospitalization.

Methods: Dutch cardiac patients who experienced a cardiac event hospitalization participated in a semi-structured interview (n = 14) or a cross-sectional survey study (n = 119).

Results: Our findings indicate that cardiac patients are receptive to lifestyle advice throughout the care trajectory.

Making sense of a myocardial infarction in relation to changing lifestyle in the five months following the event: An interpretative phenomenological analysis.

Objective: Previous research has shown that experiencing an acute cardiac event, such as a myocardial infarction (MI), can lead to lifestyle changes. This study aimed to explore the potential of a MI as a 'teachable moment' (TM) for positive lifestyle changes and to identify psychosocial sensemaking processes that facilitate or hinder the presence of a TM.

Method: We conducted semi-structured interviews with 14 patients who suffered their first MI and were hospitalized in a larger Dutch city.

Dealing with Alcohol-Related Posts on Social Media: Using a Mixed-Method Approach to Understand Young Peoples' Problem Awareness and Evaluations of Intervention Ideas.

Young individuals frequently share and encounter alcohol-related content (i.e., alcohol posts) on social networking sites.

My future-self has (not) quit smoking: An experimental study into the effect of a future-self intervention on smoking-related self-identity constructs.

Objectives: Envisioning one's (non)smoking future may make (un)desired future identities more accessible, salient, and personally relevant and facilitate smoking cessation. The current study assessed whether a future-self intervention can weaken smoker self-identity and expected identity loss when quitting smoking, and strengthen quitter- and nonsmoker self-identity, while accounting for personal factors-socioeconomic position, nicotine dependence, consideration of future consequences, and clarity of the envisioned future-self. Additionally, it examined the association between smoking-related identity and quitting intention and behavior.

Identified or conflicted: a latent class and regression tree analysis explaining how identity constructs cluster within smokers.

Identity, or 'who I am', is important for smoking behaviour. Identity constructs (parts of a person's identity) are typically examined as separate entities, but emerging evidence suggests that the multifaceted nature of identity is relevant in the context of smoking. This cross-sectional study examined how smoking-related self- and group-identity constructs cluster within adult daily smokers (N = 231), whether classes of smokers can be distinguished based on clusters of identity constructs, and which factors explain class membership.

Mapping the evidence on identity processes and identity-related interventions in the smoking and physical activity domains: a scoping review protocol.

Introduction: Smoking and insufficient physical activity (PA), independently but especially in conjunction, often lead to disease and (premature) death. For this reason, there is need for effective smoking cessation and PA-increasing interventions. Identity-related interventions which aim to influence how people view themselves offer promising prospects, but an overview of the existing evidence is needed first.

The development and validation of scales to measure the presence of a teachable moment following a cardiovascular disease event.

Better conceptually-driven research is necessary to learn more about 1) the characteristics of life events as teachable moments (TMs) and 2) the potential of life events to evoke lifestyle change intention (LCI). This study aimed to develop and validate two scales for the purposes of TM research in the context of cardiovascular disease (CVD): the and scales. After the initial development of items based on a theoretical framework and literature search, six experts rated the content validity of both scales as sufficient.

Causal Effects of Alcohol-Related Facebook Posts on Drinking Behavior: Longitudinal Experimental Study.

Background: Adolescents and young adults frequently post alcohol-related content (ie, alcoholposts) on social media. This is problematic because both social norms theory and social learning theory suggest that viewing alcoholposts of peers could increase drinking behavior. It is therefore paramount to understand the effects of exposure to alcoholposts on viewers.

The COVID-19 Crisis as a Teachable Moment for Lifestyle Change in Dutch Cardiovascular Disease Patients.

When lifestyle changes are needed, life events or crises such as COVID-19 may function as "teachable moments". This study aimed to explore whether the pandemic can provoke a teachable moment regarding lifestyle change in cardiovascular disease patients. In this cross-sectional survey study, 830 cardiovascular disease patients reported their intentions to change lifestyle, instigated by the corona crisis, together with risk perception, affective impact, and changed self-concept, based on a "teachable moments" framework.

Stakeholder Values and Preferences in Lower Limb Amputation for No-Option Chronic Limb Threatening Ischemia.

Purpose: This study focusses on identifying values and preferences of patients, caregivers and healthcare professionals who have dealt with lower limb amputation for no-option chronic limb threatening ischemia. No-option chronic limb threatening ischemia is defined as limb ischemia for which no treatment options exist and where lower limb amputation is necessary in the short term. The values and preferences identified in this study can help improve decision-making processes.

[Teachable moments: the right moment to make patients change their lifestyle].

Healthcare professionals can play a significant role in the prevention of lifestyle-related diseases. Yet there is still relatively little attention to lifestyle counseling, partly because of limited available time and doubts about its effectiveness. During so-called 'teachable moments', patients may be more receptive towards lifestyle advices and more motivated to change their lifestyle.

Self-management interventions for people with intellectual disabilities: A systematic review.

Objective: People with intellectual disabilities (ID) often experience difficulties managing their affairs. This study reviewed self-management interventions for people with mild to moderate ID, studying interventions' effectiveness and applied behavioural change techniques (BCTs).

Methods: A systematic literature search was conducted in PubMed, PsychINFO, Web of Science, Embase, Emcare, Cochrane, and ProQuest.

Picture Me Drinking: Alcohol-Related Posts by Instagram Influencers Popular Among Adolescents and Young Adults.

Research has shown that young people post a lot of alcohol-related posts (i.e., alcoholposts) on social media and these posts have been shown to increase drinking behaviors.

Identity processes in smokers who want to quit smoking: A longitudinal interpretative phenomenological analysis.

The importance of identity in smoking cessation is increasingly becoming recognized by researchers. This study is the first in-depth longitudinal qualitative investigation of identity change processes among smokers who intend to quit. Participants' accounts of smoking, attempts to quit and sense of identity were explored over time to examine identity continuity and change.

Development of the Leiden Independence Questionnaire for Support Staff: a measure of staff behaviour regarding promoting independence of people with intellectual disabilities.

Background: Support staff of adults with intellectual disability (ID) play an important role in promoting independence in home and community settings. However, little is known about the types of behaviours staff should use to promote independence and instruments that assess such behaviour do not yet exist. The aim of this study was therefore to develop and initially validate a reliable questionnaire that measures the degree to which support staff display behaviours that promote independence in people with ID.

Ozonation of valsartan: Structural elucidation and environmental properties of transformation products.

The pharmaceutical valsartan is classified as a trace organic compound and is released into wastewater from human consumption. Trace organic compounds are not completely removed during conventional wastewater treatment. In order to prevent their release into the aquatic environment, advanced wastewater treatment technologies such as ozonation are currently implemented.

Effects of a self-management training for people with intellectual disabilities.

Background: To help people with intellectual disabilities lead a more independent life, it is important to promote their self-management. This study evaluated the effectiveness of a self-management training for people with intellectual disabilities directed at independent functioning in daily life.

Method: In the training, 17 people with intellectual disabilities worked on personal self-management goals covering a wide range of everyday affairs.

Exploring the direct or inverse association of physical activity with behavioral addictions and other self-regulation problems.

This cross-sectional survey study had the aim of clarifying the relationships between leisure time physical activity (LTPA) and non-drug-re-lated self-regulation problems (non-drug-related SRPs), including behavioral addictions, and the role of impulsive personality traits therein. Spanish university students (N = 329; Mage = 21.20) completed questionnaires for each of these constructs.

Elucidation of the oxidation mechanisms and pathways of sulfamethoxazole degradation under Fe(II) activated percarbonate treatment.

Fe(II) activated sodium percarbonate (SPC) process (SPC/Fe(II)) could efficiently remove sulfamethoxazole (SMX) in the aqueous phase, and has the potential in groundwater remediation. However, the degradation mechanisms, especially the degradation products and pathways till now have remained unclear. In the present study, intermediate products were identified using high resolution liquid chromatography coupled with ion trap and time-of-flight mass spectrometry (LCMS-IT-TOF).

Alcoholposts on Social Networking Sites: The Alcoholpost-Typology.

Young people frequently display alcohol-related posts ("alcoholposts") on social networking sites such as Facebook and Instagram. Although evidence exists that such posts may be linked with increases in alcohol consumption, hardly any studies have focused on the content of such posts. This study addresses this gap by applying and extending the alcoholpost-typology previously proposed by Hendriks, Gebhardt, and van den Putte.

Social Drinking on Social Media: Content Analysis of the Social Aspects of Alcohol-Related Posts on Facebook and Instagram.

Background: Alcohol is often consumed in social contexts. An emerging social context in which alcohol is becoming increasingly apparent is social media. More and more young people display alcohol-related posts on social networking sites such as Facebook and Instagram.

Strengthening quitter self-identity: An experimental study.

Objectives: Smoking-related self-identity processes are important for smoking cessation. We examined whether quitter self-identity (i.e.

Prevalence and Psychosocial Correlates of Party-Drug Use and Associated Problems among University Students in the Netherlands.

Background: Recent developments in drug use patterns call for an investigation of current party-drug use and associated problems among college students, who appear to be an important target population for harm reduction interventions.

Objectives: In addition to reporting on party-drug use prevalence, we investigated whether initial use and continuation of party-drug use among students was associated with demographic, personality and psychosocial factors.

Methods: An online questionnaire was administered to 446 students from a Dutch university, inquiring about party-drug use, demographic characteristics, social norms and personality (big five, impulsiveness, aggression).