Two Novel, Nonoperative Methods of Stoma Prolapse in Newborns: 3 Case Reports.

Background: Prolapse is a common complication following enterostomy; the defect and consequences of a prolapse significantly affect health-related quality of life. Creative techniques must be employed to manage the prolapse.

Cases: This article describes management of 3 neonates with stoma prolapse.

New sonographic feature (C-sign) to improve the prenatal accuracy of jejunal atresia.

Objectives: To describe a new sonographic feature of the C-sign for prenatal diagnosis of jejunal atresia and evaluate its role in prenatal jejunal atresia, particularly preceding bowel dilatation and polyhydramnios.

Methods: This was a retrospective study from a tertiary maternal hospital. Patients with prenatal sonographic examination and confirmed small bowel atresia postdelivery were included.

Interleukin-6-mediated CCR9 interleukin-17-producing regulatory T cells polarization increases the severity of necrotizing enterocolitis.

Background: Increased frequency of CCR9 CD4 T cells in peripheral blood is linked to several gastrointestinal inflammatory diseases; however, its relationship with necrotizing enterocolitis (NEC) is not understood. We investigated whether the frequencies of CCR9 CD4 T cells and related subsets were increased in peripheral blood of both patients and mice with NEC.

Methods: CCR9 CD4 T cells and related subsets were evaluated by flow cytometry in peripheral blood collected from both patients and mice with NEC and controls.

[Timing investigation of single-stage definitive surgery for newborn with Hirschsprung's disease].

Objective: To investigate the operation timing of newborns with rectosigmoid Hirschsprung's disease (HD).

Methods: From March 2013 to September 2015, 35 newborns diagnosed as rectosigmoid HD in our department were prospectively and randomly divided into 2 groups: less than 3 months treatment group (18 cases) and more than 3 months treatment group (17 cases, conservative treatment for 3 months). They all underwent laparoscopic-assisted transanal endorectal pull-through (LATEP) (modified Soave) procedure.

TGF-β1, Ghrelin, Neurexin, and Neuroligin are predictive biomarkers for postoperative prognosis of laparoscopic surgery in children with Hirschsprung disease.

The study was set to analyze the predictive values of transforming growth factor β1 (TGF-β1), Ghrelin, Neurexin, and Neuroligin protein expression on postoperative prognosis of laparoscopic surgery in children with Hirschsprung disease. 281 cases of children with Hirschsprung disease, admitted into Guangdong Women and Children Hospital and Guangzhou women and children's medical center from March 2009 to March 2014, were treated with laparoscopic radical surgery for Hirschsprung disease. They were divided into the good and the poor prognosis groups according to their recuperation and complications.