Publications by authors named "Ge Pu"
Article Synopsis
- - This study examines the potential causal link between diastolic blood pressure (DBP) and Alzheimer's disease (AD) using 2-sample Mendelian randomization analysis with large genome-wide association study data and a validation sample of patients with cardiovascular disease.
- - Various statistical methods, including inverse variance weighting and MR-Egger regression, were applied to investigate the relationship; findings indicated that higher DBP may be associated with a lower risk of developing AD.
- - The analysis showed minimal pleiotropy and no heterogeneity in the data, suggesting stable results that support the hypothesis of a causal relationship between DBP and AD risk.
Application of Chatbots to Help Patients Self-Manage Diabetes: Systematic Review and Meta-Analysis.
J Med Internet Res
December 2024
Article Synopsis
- The global rise in diabetes cases highlights the importance of patient self-management and education, and chatbots may enhance this through accessible digital therapies and information.
- This study systematically reviews 25 research articles on the effectiveness of chatbots for diabetes self-management, categorizing them by study type and research strategy, including systematic design, pilot, and intervention studies.
- The majority of the reviewed chatbots focused on educating patients about diet, exercise, glucose monitoring, medications, and complications, aiming to improve technical performance, user experience, and overall health outcomes.
Article Synopsis
- A study was conducted to assess the prevalence of subthreshold depression among Chinese college students, revealing a significant rate of approximately 39.7% among 8,934 participants.
- Factors such as being female, having chronic illnesses, experiencing financial debt, facing challenges in family communication, and feeling high perceived pressure were linked to a higher risk of developing subthreshold depression.
- The research suggests that strong family communication, better perceived social support, and higher self-efficacy may serve as protective factors against subthreshold depression, highlighting the importance of timely screening for at-risk students.
The objective of this study was to investigate self-medication behavior among Chinese adolescents aged 12-18 years and explore the factors associated with whether adolescents prioritize drug efficacy or safety when engaging in self-medication behavior. In 2021, a questionnaire investigation was conducted in the Chinese mainland using a multi-stage sampling approach. After a statistical description, logistic regression was used to analyze the factors associated with considering drug efficacy and safety.
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- This study explores the link between anxiety and suboptimal health, highlighting that suboptimal health is an intermediate state between being healthy and ill.
- It involved a large sample of 26,010 participants in China, using specific assessments to measure anxiety and health symptoms, and employed network analysis to identify key symptoms.
- Key findings indicate high rates of anxiety and suboptimal health, with notable symptoms like "Decreased responsiveness" and "Uncontrollable worry" being central to the network, and the study suggests that addressing these symptoms could improve overall health outcomes.
Article Synopsis
- The study explores lung function testing behaviors among middle-aged and elderly individuals in China, emphasizing the importance of annual tests for those over 40 as per the Healthy China Initiative.
- A nationwide questionnaire survey analyzed factors influencing participation in lung function tests, using statistical methods like chi-square tests and binary logistic regression.
- Key findings indicate that education level, ability to afford healthcare, health status (based on the European Five Dimensional Health Scale), and self-efficacy significantly affect the likelihood of participating in lung function testing, highlighting a need for increased awareness and accessibility.
Article Synopsis
- Aflibercept, used for metastatic colorectal cancer, has unclear antiangiogenesis-related side effects, prompting a systematic review of its adverse events when combined with chemotherapy.
- The study included data from 2889 patients across 10 trials and showed notable adverse effects such as hypertension (44.2%) and proteinuria (31.3%) in single-arm studies, with higher risks noted in randomized controlled trials for hypertension and proteinuria.
- Statistical analyses confirmed the increased incidence rates of serious adverse events in patients treated with aflibercept, highlighting the need for careful monitoring during treatment.
Background: The application of virtual reality (VR) in gastroscopic operation teaching can be safe and effective, but the advantages can be realized only when students accept and use it. This study aims to identify the factors influencing Chinese clinical medical postgraduates on their intention to use the 3D gastroscopic model constructed based on VR technology using Unified Theory of Acceptance and Use of Technology (UTAUT) model. Students' demographic factors are also taken into consideration.
View Article and Find Full Text PDFMalignant melanoma is a highly aggressive cancer that spreads and metastasizes quickly. In recent years, the antiangiogenic drug bevacizumab has been trialed to treat malignant melanoma. We conducted the first meta-analysis to examine the efficacy and safety of bevacizumab combined with other drugs in malignant melanoma.
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- * A numerical simulation model was developed to analyze the pressure distribution and flow characteristics of supercritical CO jets, confirming the model's reliability.
- * The study found that the jet's state (fully expanded vs. under-expanded) significantly affects pressure distribution, especially under certain nozzle pressure ratios and distances from the wall.
Article Synopsis
- * A survey of 625 college students revealed that factors such as hometown, monthly expenses, and parents’ smoking history significantly affected their tobacco control intentions and behaviors, with performance expectancy and social influence showing direct positive effects.
- * The study suggests that enhancing students' expectations and e-health literacy, fostering supportive social environments, and improving conditions for tobacco control are crucial for curbing smoking rates among non-smokers, while also advocating for smoke-free campus initiatives.
Background: This study explored the effects of personality factors on public behavioral decision-making.
Methods: We examined the literature on personality theory based on triadic interaction decision theory, and summarized and compared the findings with studies of the Big Five personality characteristics. A literature review method was used to explore the implications of personality theory for public decision-making in Chinese communities.
Article Synopsis
- The study addresses the rising obesity rates in China and the need for a reliable tool to measure obesity-related eating behaviors, specifically translating the 7-item EBS-SF into Chinese.
- The translation process involved surveying 3,440 residents and performing reliability and validity tests, confirming that the scale is both sound and effective.
- Results indicated that the Chinese EBS-SF has good structural validity and reliability; its scores correlate with factors like personality, family health, and depression, making it a useful tool for evaluating eating behaviors in the Chinese population.
Article Synopsis
- * The most commonly purchased OTC medications were paracetamol and analgesics, with key considerations for self-medication being medical recommendations, drug safety, and efficacy.
- * Data was collected from over 9,000 respondents across various regions in China, with analysis revealing significant trends in how residents prioritize drug safety and effectiveness based on their demographic and healthcare access factors.
Article Synopsis
- Health literacy is important for understanding health status, but there is a lack of a standardized brief health literacy scale for the general population in China.
- The 12-item HLS-SF12 scale was translated into Chinese and tested for validity and reliability using a sample of 10,951 residents.
- Results showed high reliability (Cronbach's Alpha of 0.94) and good validity, indicating that the Chinese version of the HLS-SF12 can effectively evaluate health literacy among Chinese people.
Background: HPV vaccine can block the infection of high-risk human papillomavirus and is an important measure to effectively reduce the incidence of cervical cancer and precancerous lesions. However, the HPV vaccination rate is still low in China. There are many factors.
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- The study looked at how Chinese people buy over-the-counter (OTC) drugs and what influences their decisions.
- Most people (99.06%) self-medicate, often purchasing drugs like NSAIDs (pain relievers) and vitamins.
- Many respondents (86.2%) consider advice from medical staff important when choosing OTC drugs, especially women and those with certain personality traits and health literacy.
Article Synopsis
- Subthreshold depression can lead to major depression, and psychotherapy is an intervention that has been reviewed for its effectiveness, although no comprehensive overview exists yet.
- This study aims to review existing systematic reviews and meta-analyses to assess the efficacy of psychotherapy specifically for individuals with subthreshold depression.
- The researchers will evaluate the quality of the studies and present their findings to help inform future treatment strategies for subthreshold depression.*
College Students' Degree of Support for Online Learning during the COVID-19 Pandemic and Associated Factors: A Cross-Sectional Study.
Int J Environ Res Public Health
December 2022
Article Synopsis
- During the COVID-19 pandemic, educational institutions worldwide shifted to online teaching, but limited research has examined Chinese college students' support for this mode of learning.
- A study involving 9,319 students found that over half of them were supportive of online learning, with factors like depression negatively impacting support while family communication and social support had positive effects.
- The research highlighted the importance of addressing mental health and suggested that enhancing family communication and social support could improve students' attitudes toward online learning.
The current status and factors related to the preparation of home first-aid kits in China.
Front Public Health
December 2022
Background: Home first-aid kits can play an important role when residents are injured, suddenly become seriously ill or suffer from disasters.
Purpose: To explore the home first-aid kit preparedness of Chinese residents and the relationship between demographic sociological characteristics, self-efficacy, Big Five personality, health literacy and home first-aid kit preparation behavior.
Methods: A cross-sectional study was conducted.
Lifestyles and health-related quality of life in Chinese people: a national family study.
BMC Public Health
November 2022
Background: There were few studies that investigated health-related quality of life (HRQoL) of the general population in China, and many of them reported limitations in sampling.
Objective: To investigate the relationship between lifestyles and HRQoL in the Chinese population in both individual and family levels.
Method: Online questionnaires were distributed across China to collect demographic information and participants' HRQoL using EuroQoL 5 Dimension scales.
Article Synopsis
- - Self-medication is increasingly common in China, and this study aimed to assess the behavior and factors influencing it, particularly regarding medical insurance reimbursement and drug prices.
- - A survey was conducted with over 9,000 respondents, revealing that 37.52% prioritize drug prices and 28.53% value medical insurance reimbursement when purchasing OTC drugs, with various demographic influences highlighted.
- - The findings indicated that older individuals with insurance and lower health literacy are more likely to consider reimbursement, while students and those with higher family incomes tend to overlook both reimbursement and drug prices.
Article Synopsis
- * Data was collected from 693 Chinese adolescents aged 12-18, highlighting issues like unsafe walking, poor eating habits, and exposure to violence as prevalent health risks.
- * The findings show smartphone use can delay the onset of alcohol consumption but has a negative relationship with unsafe walking behaviors, with family health serving as an indirect mediator in this context.