Bt toxins alter bacterial communities and their potential functions in earthworm intestines.

The accumulation and persistence of Bt toxins in soils from Bt plants and Bt biopesticides can result in ecological hazards. Earthworms are one of the most frequently used bioindicators for soil ecological monitoring, characterization, and risk assessment. However, the effects of Bt toxins on earthworm bacterial communities have conversely rarely been studied.

Ni Vacancy and the Se/S Ratio Regulate the p-Band Center of Hollow NiSSe/Phase Junction CdS to Achieve High Efficiency and Broad-Spectrum Photocatalytic Performance.

Rational design of defect engineering and interfacial built-in electric fields of photocatalysts is imperative for renewable energy conversion. Herein, a multi-strategy involving the introduction of Ni vacancies, the adjustment of the Se/S ratio, and the construction of dual junctions are employed to simultaneously realize NiSSe/phase junction CdS (HCC) an excellent photocatalytic activity and broad light absorption. With the help of V and the regulation of S/Se, the local electrons are redistributed to occupy more antibonding orbitals and adjust the p-band center, thus optimizing the H adsorption energy of the catalyst to accelerate the photocatalytic reaction kinetics.

Non-selective Defect Minimization towards Highly Efficient Metal-Organic Framework Membranes for Gas Separation.

The persistence of defects in polycrystalline membranes poses a substantial obstacle to reaching the theoretical molecular sieving separation and scaling up production. The low membrane selectivity in most reported literature is largely due to the unavoidable non-selective defects during synthesis, leading to a mismatch between the well-defined pore structure of polycrystalline molecular sieve materials. This paper presents a novel approach for minimizing non-selective defects in metal-organic framework (MOF) membranes by a constricted crystal growth strategy in a confined environment.

Enzyme-Mimetic, Cascade Catalysis-Based Triblock Polypeptide-Assembled Micelles for Enhanced Chemodynamic Therapy.

Peptides and their conjugates are appealing as molecular scaffolds for constructing supramolecular biomaterials from the bottom up. Through strategic sequence design and interaction modulation, these peptides can self-assemble into diverse nanostructures that can, in turn, mimic the structural and catalytic functions of contemporary proteins. Here, inspired by the histidine brace active site identified in the metalloenzyme, we developed a triblock polypeptide with a hydrophobic polyleucine segment, a hydrophilic polylysine segment, and a terminal oligohistidine segment.

DaxibotulinumtoxinA for injection to treat moderate or severe glabellar lines: A randomized, multicenter, Phase III, double-blind, placebo-controlled trial in China.

Background: DaxibotulinumtoxinA for injection (DAXI), a novel botulinum toxin type A formulation, is FDA-approved for glabellar lines treatment. Its clinical efficacy has been demonstrated in two Phase III trials (SAKURA 1 and SAKURA 2).

Objective: To evaluate DAXI efficacy and safety in Chinese adults with moderate/severe glabellar lines.

Fabrication and Self-Assembly Behavior of BPEF and BBPEF Composite Langmuir-Blodgett Films with Photovoltaic Conversion Properties.

The LB films prepared through the Langmuir-Blodgett (LB) technique are of significant importance for the fabrication of functional films such as optoelectronic materials and sensors. In this study, 9,9-bis (4-(2-hydroxy-ethoxy) phenyl) fluorene (BPEF) and 9,9-bis [3-phenyl-4-(β-hydroxy-ethoxy) phenyl] fluorene (BBPEF) were combined with saffron T (ST), methylene blue (MB) and Rhodamine B (RhB) dyes by LB technique to prepare ordered composite films. The nanostructures and morphologies of the composite films were analyzed by transmission electron microscopy (TEM) and atomic force microscopy (AFM).

Dopamine-assisted surface functionalization of saccharide-responsive fibers for the controlled harvesting and continuous fermentation of Saccharomyces cerevisiae.

Continuous fermentation processes increasingly emphasized cell recycling, utilization, and renewal. In this study, to improve the sustainability of the immobilized Saccharomyces cerevisiae, the cells were recovered on the surface of the glucose-responsive supports through manipulating the competitive interactions of phenylboric acid groups between glycoproteins on the cells and glucose. Through a dopamine (DA)-assisted deposition approach, 3-acrylamidophenylboronic acid (APBA) was integrated to design the saccharide-sensitive cotton fibers (APBA@PDA-CF).

Rational Designing Microenvironment of Gas-Diffusion Electrodes via Microgel-Augmented CO Availability for High-Rate and Selective CO Electroreduction to Ethylene.

Efficient electrochemical CO reduction reaction (CORR) requires advanced gas-diffusion electrodes (GDEs) with tunned microenvironment to overcome low CO availability in the vicinity of catalyst layer. Herein, for the first time, pyridine-containing microgels-augmented CO availability is presented in CuO-based GDE for high-rate CO reduction to ethylene, owing to the presence of CO-phil microgels with amine moieties. Microgels as three-dimensional polymer networks act as CO micro-reservoirs to engineer the GDE microenvironment and boost local CO availability.

Ruthenium Anchored Laser-Induced Graphene as Binder-Free and Free-Standing Electrode for Selective Electrosynthesis of Ammonia from Nitrate.

Developing effective electrocatalysts for the nitrate reduction reaction (NORR) is a promising alternative to conventional industrial ammonia (NH) synthesis. Herein, starting from a flexible laser-induced graphene (LIG) film with hierarchical and interconnected macroporous architecture, a binder-free and free-standing Ru-modified LIG electrode (Ru-LIG) is fabricated for electrocatalytic NORR via a facile electrodeposition method. The relationship between the laser-scribing parameters and the NORR performance of Ru-LIG electrodes is studied in-depth.

Experimental investigation on coupled-bunch instability and suppression for the upgrade of Beijing Electron-Positron Collider (BEPCII).

After touching the design collision luminosity of 1.0 × 1033 cm-2 s-1 in 2016, this target has not been reached again for the upgrade of Beijing Electron-Positron Collider during physical collision operation in subsequent years due to various factors, such as the collision background, noise, and equipment stability under high power operation. One of the most serious factors was the beam instability, especially the coupled-bunch instability, whose sideband distribution was clearly displayed on the spectrum analyzer when the feedback system was OFF.

Synergistic dual built-in electric fields in 1T-MoS/NiS/LDH for efficient electrocatalytic overall water splitting reactions.

Designing cost-effective electrocatalysts for water decomposition is crucial for achieving environmental-friendly hydrogen production. A transition metal sulfide/hydroxide electrocatalyst (1T-MoS/NiS/LDH) with double heterogeneous interfaces was developed through a two-step hydrothermal assisted electrodeposition method. The presence of the two built-in electric fields not only accelerated the charge transfer at the interface, but also enhanced the adsorption of the reactants and intermediate groups, and therefore improved the reaction rate and overall catalytic performance.

Intrinsically reactive hyperbranched interface governs graphene oxide dispersion and crosslinking in epoxy for enhanced flame retardancy.

Enhancing the flame retardancy of epoxy (EP) resins typically entailed a trade-off with other physical properties. Herein, hyperbranched poly(amidoamine) (HPAA) and phytic acid (PA) were used to functionalize graphene oxide (GO) via electrostatic self-assembly in water to prepare a phosphorus-nitrogen functionalized graphene oxide nanosheet (PN-GOs), which could be utilized as high efficient flame-retardant additive of epoxy resin without sacrificing other properties. The PN-GOs demonstrated improved dispersion and compatibility within the EP matrix, which resulted in significant concurrent enhancements in both the mechanical performance and flame-retardant properties of the PN-GOs/EP nanocomposites over virgin EP.

Comprehensive analysis of the complete mitochondrial genome of Lilium tsingtauense reveals a novel multichromosome structure.

Lilium tsingtauense mitogenome comprises 27 independent chromosome molecules, it undergoes frequent genomic recombination, and the rate of recombination and mutation between different repetitive sequences affects the formation of multichromosomal structures. Given the extremely large genome of Lily, which likely harbors additional genetic resources, it serves as an ideal material for studying the phylogenetic evolution of organisms. Although the Lilium chloroplast genome has been documented, the sequence of its mitochondrial genome (mitogenome) remains uncharted.

Nanoplastics induced health risk: Insights into intestinal barrier homeostasis and potential remediation strategy by dietary intervention.

Aged nanoplastics (aged-NPs) have unique characteristics endowed by environmental actions, such as rough surface, high oxygen content. Although studies have highlighted the potential hazards of aged-NPs, limited research has provided strategies for aged-NPs pollution remediation. The dietary intervention of quercetin is a novel insight to address the health risks of aged-NPs.

Portable and Flexible Hydrogel Sensor for On-Site Atrazine Assay on Agricultural Products.

There is growing attention focused toward the problems of ecological sustainability and food safety raised from the abuse of herbicides, which underscores the need for the development of a portable and reliable sensor for simple, rapid, and user-friendly on-site analysis of herbicide residues. Herein, a novel multifunctional hydrogel composite is explored to serve as a portable and flexible sensor for the facile and efficient analysis of atrazine (ATZ) residues. The hydrogel electrode is fabricated by doping graphite-phase carbon nitride (g-CN) into the aramid nanofiber reinforced poly(vinyl alcohol) hydrogel via a simple solution-casting procedure.

Electrochemical control of the morphological evolution of PEDOT on a Ni-Co(OH)/carbon cloth surface to modulate the performance of wearable HO sensors.

The slow redox rate of hydrogen peroxide (HO) in neutral environments makes the HO sensor inadequate for the detection of low levels of signalling molecules. The aim of this study is to fabricate a flexible sensing electrode by hydrothermally loading micro-nanometer Ni and Co(OH) on carbon cloth (CC) and electrochemically depositing poly(3,4-ethylenedioxythiophene) (PEDOT) on the surface of the electrode. The sensor presented high sensitivity (10.

Hollow cubic CuSe@CdS with tunable size for plasmon-induced Vis-NIR driven photocatalytic properties.

The rational design of the dimension and geometry of a plasmonic semiconductor cocatalyst is vitally important for efficient utilization of near-infrared (NIR) light and superior photocatalytic hydrogen generation. Herein, hollow cubic CuSe@CdS composites with different sizes and strong localized surface plasmon resonance (LSPR) were prepared by selenizing size-tunable CuO templates and loading CdS nanoparticles. The size of hollow cubic CuSe can affect the surface area and the conduction band potential through the size effect, regulating the carrier behavior of the CuSe@CdS heterojunction.

Pivotal role of heterotrimeric G protein in the crosstalk between sugar signaling and abiotic stress response in plants.

Heterotrimeric G-proteins are key modulators of multiple signaling and developmental pathways in plants, in which they act as molecular switches to engage in transmitting various stimuli signals from outside into the cells. Substantial studies have identified G proteins as essential components of the organismal response to abiotic stress, leading to adaptation and survival in plants. Meanwhile, sugars are also well acknowledged key players in stress perception, signaling, and gene expression regulation.

Associations between obesity and hyperuricemia combing mendelian randomization with network pharmacology.

Objective: Obesity has become a global health issue and a risk factor for hyperuricemia. However, the associations between obesity and hyperuricemia are sometimes confounding. In the present study, we performed mendelian randomization (MR) analysis to study their relationship and investigate the underlying mechanism by network pharmacology.

SlWRKY81 regulates Spd synthesis and Na/K homeostasis through interaction with SlJAZ1 mediated JA pathway to improve tomato saline-alkali resistance.

Saline-alkali stress is an important abiotic stress factor affecting tomato (Solanum lycopersicum L.) plant growth. Although the involvement of the tomato SlWRKY gene family in responses to saline-alkali stress has been well established, the mechanism underlying resistance to saline-alkali stress remains unclear.

Simultaneous variable selection and estimation in semiparametric regression of mixed panel count data.

Mixed panel count data represent a common complex data structure in longitudinal survey studies. A major challenge in analyzing such data is variable selection and estimation while efficiently incorporating both the panel count and panel binary data components. Analyses in the medical literature have often ignored the panel binary component and treated it as missing with the unknown panel counts, while obviously such a simplification does not effectively utilize the original data information.

Glycyrrhizin alleviates radiation-induced lung injury by regulating the NLRP3 inflammasome through endoplasmic reticulum stress.

Objective: Radiation pneumonitis (RP) is the major adverse response of radiation therapy for thoracic malignant tumors, and there is a lack of effective interventions. The aim of this study was to investigate the radioprotective effect of Glycyrrhizin (GL) on RP and its potential mechanism.

Method: The body weight and lung weight of mice were monitored.

Displaying epistemic stance through same-turn self-repair in Chinese civil courtroom interaction.

Repair, or conversational repair, frequently appears in court proceedings as a vital mechanism sustaining effective communication. Our study presents a conversational analysis of the choices of different operations in the same-turn self-repair and shows how judges, plaintiffs, defendants, and their lawyers deploy those operations based on a model of epistemic stance. The data were drawn from the top five most-viewed videos of Changsha civil courtrooms from March to May, 2019, totaling more than 50,000 words.

A light-activatable theranostic combination for ratiometric hypoxia imaging and oxygen-deprived drug activity enhancement.

While performing oxygen-related tumour treatments such as chemotherapy and photodynamic therapy, real-time monitoring hypoxia of tumour is of great value and significance. Here, we design a theranostic combination for light-activated ratiometric hypoxia imaging, hypoxia modulating and prodrug activation. This combination consisted of an oxygen-sensitive near-infrared-emitting ratiometric phosphorescence probe and a hypoxia-activated prodrug-loaded covalent organic framework.