Milk consumption and bone mineral content in Chinese adolescent girls.

A cross-sectional study of a random sample of 649 girls, aged 12-14 years (mean +/- SD: 12.9 +/- 0.6 years), in the Beijing area examined the relationship between diet and bone mineral status.

Dietary intake of some essential micronutrients in China.

Objective: Based on the data collected in the 1992 national nutrition survey in China, the food consumption and nutrients intake were calculated, and the consumption of some micronutrients was evaluated.

Method: Dietary data were obtained by using a three days' inventory change plus food weighing in combination with 24 hours recall method for three consecutive days. The food consumption and nutrients intake were calculated in accordance with the Chinese food composition table.

Definition and measurement of child malnutrition.

Child Malnutrition has been defined or described in many ways. To summarize the common points, child malnutrition may be defined as a pathological state resulting from inadequate nutrition, including undernutrition (protein-energy malnutrition) due to insufficient intake of energy and other nutrients; overnutrition (overweight and obesity) due to excessive consumption of energy and other nutrients; deficiency diseases due to insufficient intake of one or more specific nutrients such as vitamins or minerals. In the assessment of child malnutrition, a large number of measures are available.

Intrahousehold food distribution: a case study of eight provinces in China.

A longitudinal survey of health and nutrition in China was undertaken in eight provinces (Liaoning, Jiangsu, Shandong, Henan, Hubei, Hunan, Guangxi, Guizhou). Data were collected in 1989, 1991, 1993 and 1997. The 1991 and 1993 data were used to investigate factors affecting intrahousehold food distribution.

Vitamin D deficiency and associated factors in adolescent girls in Beijing.

Background: Several locally published reports indicate a high prevalence of vitamin D deficiency among adolescents in China, but no systematic population-based survey has been conducted.

Objective: The objective was to determine the prevalence of vitamin D deficiency and to study associated factors in adolescent girls in Beijing.

Design: A cross-sectional study was conducted in a random sample of 1248 Beijing girls aged 12-14 y.

Weight gain and its predictors in Chinese adults.

Objective: To describe 8 y weight change in Chinese adults and to determine the baseline characteristics of those who gained weight.

Design: A population-based cohort study of weight change and its predictors from 1989 to 1997.

Participants: A cohort of 2488 adults aged 20-45 in 1989 drawn from seven provinces in China using multistage, random cluster sampling.

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program.

Cell death processes are progressively inactivated during malignant development, in part by loss of tumor suppressors that can promote cell death. The Bin1 gene encodes a nucleocytosolic adaptor protein with tumor suppressor properties, initially identified through its ability to interact with and inhibit malignant transformation by c-Myc and other oncogenes. Bin1 is frequently missing or functionally inactivated in breast and prostate cancers and in melanoma.

Tracking of body mass index from childhood to adolescence: a 6-y follow-up study in China.

Background: Although extensive descriptive research shows that childhood obesity predisposes a person to adult obesity, little is understood about the dynamics of weight during childhood and the predictors of weight tracking.

Objective: Our objective was to examine tracking patterns of body mass index (BMI) as well as their predictors between childhood and adolescence.

Design: A cohort of 975 Chinese children aged 6-13 y was followed for 6 y (1991-1997).

Bin2, a functionally nonredundant member of the BAR adaptor gene family.

BAR family proteins are a unique class of adaptor proteins characterized by a common N-terminal fold of undetermined function termed the BAR domain. This set of adaptors, which includes the mammalian proteins amphiphysin and Bin1 and the yeast proteins Rvs167p and Rvs161p, has been implicated in diverse cellular processes, including synaptic vesicle endocytosis, actin regulation, differentiation, cell survival, and tumorigenesis. Here we report the identification and characterization of Bin2, a novel protein that contains a BAR domain but that is otherwise structurally dissimilar to other members of the BAR adaptor family.

Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma.

The genetic events underlying the development of prostate cancer are poorly defined. c-Myc is often activated in tumors that have progressed to metastatic status, so events that promote this process may be important. Bin1 is a nucleocytoplasmic adaptor protein with features of a tumor suppressor that was identified through its ability to interact with and inhibit malignant transformation by c-Myc.

Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity.

Oncogenic activation of MYC occurs often in breast carcinoma and is associated with poor prognosis. Loss or inactivation of mechanisms that restrain MYC may therefore be involved in tumor progression. In this study, we show that the MYC-interacting adaptor protein BIN1 is frequently missing in malignant breast cells and that this loss is functionally significant.

Measuring diet quality in china: the INFH-UNC-CH diet quality index.

Objective: This paper describes the development and efficacy of a diet quality index (DQI) for China.

Design: The Dietary Guidelines for Chinese Residents motivated the selection of 10 DQI components. These components were weighted and assigned cut-offs and point schemes based on the Chinese Food Guide Pagoda, Chinese and/or international dietary reference values.

Sex difference in measures of body fatness and the possible difference in the effect of dietary fat on body fatness in men and women.

Objectives: To examine the sex difference in anthropometric measures of body fatness and to explore the possibility that diet may have differential effects on body fatness in men and women.

Design: Prospective study design.

Setting: The first and second China Health and Nutrition Survey conducted in 1989 and 1991, respectively.

Mechanism for elimination of a tumor suppressor: aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma.

Loss of tumor suppressors that restrain important oncoproteins such as c-Myc may contribute to malignant progression. Bin1 is an adapter protein with features of a tumor suppressor that was identified through its interaction with and inhibition of the oncogenic properties of c-Myc. In this study, we analyzed the patterns of Bin1 expression in normal melanocytes and melanoma cells at different stages of tumor progression.

Body mass index as predictor for body fat:comparison between Chinese and Dutch adult subjects.

The relation between body mass index (kg/m2) and body fat from body density was compared in a group of Chinese and Dutch healthy subjects in relation to sex and age. The Dutch group was selected in relation to the Chinese group in that age, weight, height and body mass index did not exceed the maximal observed values of the Chinese subjects. Mean weight, height and body mass index was higher in the Dutch group, but body fat from density did not differ between the groups.

Transduction of cytosine deaminase gene makes rat glioma cells highly sensitive to 5-fluorocytosine.

To investigate the potential use of E. coli cytosine deaminase (CD) gene instead of the commonly used HSV-TK gene in the gene therapy of brain tumors, we constructed a retrovirus vector carrying the CD gene. We then transduced a rat glioma cell line C6 with CD gene by the retrovirus vector.

Effect of nationality on dietary pattern and meal behavior in China.

In 1992 a national nutrition survey was conducted in China in approximately 100,000 people of all ages selected with use of a multistage, stratified, random, clustered procedure. Dietary data were collected with three consecutive 24-h recalls. A total of 9304 members of 20 minority nationality groups were included in the survey, accounting for 9.

Palm oil diet may benefit mildly hypercholesterolaemic Chinese adults.

The effects on serum lipids and platelet function of diets prepared with palm oil (PA) and peanut oil (PE) were studied in two groups of mild hypercholesterolaemic volunteers (serum TC between 5.5 - 7.0 mmol/L, aged 32-68).

[Effects of different form calcium on growth and tissue calcium level in rats].

In order to solve the problem of calcium deficiency and to look for economic and efficient source of calcium, the effects of calcium carbonate, active calcium and calcium lactate on growth, development and tissue calcium level in rats were compared. Fifty-six 3-week old weaning rats were fed with calcium deficient diet (containing vitamin D 500 IU per kg diet) for 3 weeks, and then were divided into four groups randomly with 14 rats in each group, half male and half female. The diet of control group (A) was the basic diet, while the three experiment diets were supplemented with calcium carbonate (B), active calcium (C) and calcium lactate (D) (3000 mg calcium per kg diet), respectively.

Expression of Cytosine Deaminase Gene in Human Colon Carcinoma Cells by Recombinant Retroviral Vector.

The recombinant retroviral vector pLCDSN containing E. coli cytosine deaminase gene was constructed. After packaging with PA317 cell line, the infectious particles were used to infect human colon carcinoma cell line LoVo.