Sodium butyrate ameliorates mitochondrial oxidative stress and alterations in membrane-bound enzyme activities in pentylenetetrazole-induced kindling rat model.

Epilepsy is a chronic neurological disorder manifested through repeatedly recurrent unprovoked seizures. It is a debilitating neurological illness arising from exacerbated hypersynchronous neuronal firing in the brain. Among various factors, oxidative stress has been implicated in the initiation of epileptogenesis and the progression of epileptic seizures.