Publications by authors named "Gazin P"

Warnings against predatory journals get stronger. Designed to capture manuscripts with the promise of rapid publication, the main aim of these journals is to charge abusive publication fees. Sometimes boasting imaginary impact factors, they are not indexed and offer no guarantee of visibility, accessibility or durability of the published article.

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The observation of miasmas and fevers was attested in the region of Biguglia, South of Bastia, in 1499, confirmed during the 17 century. Drainage works on the eastern coast were started in 1770, abandoned during the revolutionary period, restarted under the Second Empire, with few results on the endemic. Thus in 1875, 80% of the inhabitants of the eastern plain were considered on their appearance to suffer malaria.

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A mobile care unit has been designed for infectious patients care in a humanitarian setting. Six individual compartments are grouped together in the main tent of 54 m under negative air pressure. The principle of walking from clean to dirty is respected.

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The province of Equateur in the north-west of the Democratic Republic of the Congo (DRC) experienced a new Ebola outbreak in 2020. Among the responses, the actions of prevention and control of the infections were essential, particularly in health facilities. They need to be developed from a long-term perspective and not as a one-off emergency response.

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Background: In October 2010, Haiti was struck by a large-scale cholera epidemic. The Haitian government, UNICEF and other international partners launched an unprecedented nationwide alert-response strategy in July 2013. Coordinated NGOs recruited local rapid response mobile teams to conduct case-area targeted interventions (CATIs), including education sessions, household decontamination by chlorine spraying, and distribution of chlorine tablets.

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According to WHO recommendations, antimalarial drugs should be used only after a biological confirmation of a malaria attack. In order to better understand the diagnosis decision-making and the use of the malaria tests (immunochromatographic test RDT and direct microscope observation), a survey was carried out in two health facilities in the city of Cabinda, Angola in 2014. Diagnosis and drug prescriptions by the health staff were observed in 787 febrile children.

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Antimalarial drug offerings in the city of Cabinda (Angola) were assessed during the fourth quarter of 2016. Combinations of artemisinin with other effective antimalarial drugs were available free of charge in public health centres, theoretically after a biological validation of the diagnosis of a malaria attack. Private pharmacies offered many products without medical prescription, most of them being ACT (Artemisinin Combined Therapy) but some being Artemisia derivatives alone.

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Cholera, present in Haiti since October 2010, persisted in early 2014 in several places, each with its own particular epidemiological characteristics. The scarcity of fresh water probably contributed to the spread of the disease in some rural areas. Population gatherings in places without an access to either safe water or sanitation infrastructure were another factor.

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Background: On October 21, 2010, Haiti was struck by a cholera epidemic for the first time in over a century. Epidemiological and molecular genetic data have clearly demonstrated that the bacterium was imported. Nevertheless, the persistence of the epidemic for more than two years, the high incidence rates in some coastal areas and the seasonal exacerbations of the epidemic during the rainy seasons have prompted us to examine the levels of toxigenic Vibrio cholerae in the Haitian aquatic environment.

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Background: Since the beginning of the cholera epidemic in Haiti, attack rates have varied drastically with alternating peak and lull phases, which were partly associated with the fluctuating dry, rainy and cyclonic seasons. According to a study conducted in 2012, the toxigenic V. cholerae O1 strain responsible for the outbreak did not settle at a significant level in the Haitian aquatic environment.

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Cholera, that had been present in rural areas north of Port-au-Prince, Haiti since October 2010, reached the urban area in November. Due to the novelty of the disease in this region, to the lack of health care, clean water, and waste disposal facilities, and to the extensive damage caused by the earthquake on January 12, 2010, that left a large victim population living in camps, a large-scale health disaster was feared. However, after two months, the disease appeared to be relatively well-controlled and treated with a fatality rate of less than 1% in the urban area.

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Provision of basic health care to earthquake victims in camps in Haiti indicated that the population was in relatively good health. It also allowed early detection of possible epidemic outbreak.

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The role of a rapid diagnostic test (RDT) in the case management of Plasmodium falciparum malaria infections has not been determined in Africa. Our study was conducted during November 2007-January 2008 to assess test accuracy of an RDT in the management of febrile outpatients in a peripheral urban health facility in Cameroon. We found the overall sensitivity to be 71.

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Nine of 26 French tourists developed malaria after a 2-week stay under field conditions in a highly endemic place in Burkina Faso. A study of their preventive antimalarial measures identified a strong association of malaria attack with absence or inadequacy of chemoprophylaxis but not with mechanic measures.

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Background: There is little published information available describing rabies pre- and postexposure prophylaxis (PEP) in tourists returning to their home country and seeking care for animal-associated injuries, especially those associated with a rabies risk.

Method: We analyzed 261 travelers seeking care on returning to their home country following an animal-related injury acquired abroad. Information on individual cases of rabies (PEP) including preexposure status, type of contact with a potentially rabid animal, type of animal, and the nature of rabies PEP was collected by retrospectively analyzing records from May 1997 to May 2005.

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In 2003 the NGO Médecins sans Frontières started an anti-viral drug treatment program for HIV/AIDS patients in the regional hospital of Kompong Cham, Cambodia. In 2005 a total of 1100 adults and 149 children were on the active list. Sixty percent of new patients were at WHO stages 3 or 4.

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Background: Increased travel to exotic destinations around the world is escalating the risk of exposure to animal-associated injuries with a risk of acquiring rabies.

Methods: We have examined data reported to GeoSentinel Surveillance Network to highlight characteristics of animal-associated injuries in travellers.

Results: A total of 320 cases were reported from 1998 to 2005.

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Real-time PCR diagnosis of malaria has advantages over traditional microscopic methods, especially when parasitaemia is low and when dealing with mixed infections. We have developed a new real-time PCR with specific genes in each Plasmodium species present only in one copy to identify the four pathogenic Plasmodium spp. for humans.

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Background: Febrile travelers may pose a diagnostic challenge for Western physicians who are frequently involved in the assessment of these patients but unfamiliar with tropical diseases. Evaluation of this situation requires an understanding of the common etiologies, which are associated with the demographics of travelers and the destinations.

Methods: We conducted a 5-year prospective observational study on the etiologies of fever in travelers returning from the tropics admitted to the infectious and tropical diseases unit of a university teaching hospital in Marseilles, France.

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In a rural area of intense and permanent malaria transmission in Southwest Côte-d'lvoire, traditional midwifes of the Yacouba ethnic group, with also an important function for the children health and care, were interviewed in 2002 about their knowledge of the infantile pathologies. Their nosology is greatly based on symptoms and etiologic explanations of the disorder of secretions. The accumulation of a viscous liquid in different parts of the body, especially in the chest, the throat or the head, explains numerous febrile or afebrile diseases, including malnutrition.

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