Publications by authors named "Gaye Tanrioever"
Article Synopsis
- Microglial dysfunction is a significant aspect of Alzheimer’s disease, yet the specific changes in microglia's protein composition during the disease progression are not well understood.
- This study conducted a detailed analysis of protein changes in microglia from two different mouse models of Alzheimer’s, focusing on how these changes vary at different disease stages.
- Researchers discovered unique protein profiles related to microglial responses to amyloid β deposition, emphasizing that the presence of fibrillar Aβ triggers specific microglial changes, which could serve as potential biomarkers for tracking Alzheimer’s progression or evaluating treatments.
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