Promotion of Cardiovascular Health in Africa: The Alliance for Medical Research in Africa (AMedRA) Expert Panel.

This proposed scientific statement is focused on providing new insights regarding challenges and opportunities for cardiovascular health (CVH) promotion in Africa. The statement includes an overview of the current state of CVH in Africa, with a particular interest in the cardiometabolic risk factors and their evaluation through metrics. The statement also explains the main principles of primordial prevention, its relevance in reducing noncommunicable disease and the different strategies that have been effective worldwide.

PREVALENCE OF HYPERTENSION IN OUTPATIENT CONSULTATIONS IN A CARDIOLOGY DEPARTMENT IN WEST AFRICA IN DAKAR, SENEGAL ACCORDING TO "MY MEASURE MONTH".

Introduction: Hypertension is a significant public health concern globally, particularly in developing countries undergoing epidemiological transitions.

Objectives: This study, part of the "My Measure Month" program in collaboration with the French Society of Hypertension, aimed to investigate the prevalence of hypertension and stress the importance of blood pressure measurement.

Methodology: This was an observational and cross-sectional study conducted over one month in the outpatient department of a center specialized in hypertension management.

EPIDEMIOLOGY OF CARDIOVASCULAR MORTALITY IN PATIENTS UNDER 60 YEARS IN A CARDIOLOGY DEPARTMENT: A STUDY OF 73 CASES IN DAKAR, SENEGAL.

Introduction: In-hospital mortality is a critical indicator of healthcare quality, although most hospital deaths result from unavoidable morbid processes.

Objectives: This study aimed to examine cardiovascular mortality in working-age patients by analysing epidemiological, clinical, and paraclinical characteristics and identifying the key etiological factors associated with mortality.

Methodology: A descriptive and analytical retrospective study was conducted from September 2019 to August 2022 at the General Hospital Idrissa POUYE in Dakar.

COMPARATIVE STUDY BETWEEN DIABETIC AND NONDIABETIC CORONARY PATIENTS IN CARDIOVASCULAR REHABILITATION IN DAKAR, SENEGAL.

Introduction: Cardiac rehabilitation is crucial in managing coronary disease, particularly in type 2 diabetes, yet it remains almost non-existent in West Africa.

Objectives: This study aimed to compare the profiles of diabetic and non-diabetic coronary patients undergoing cardiac rehabilitation at the Principal Hospital of Dakar, Senegal.

Methodology: A comparative, descriptive, and analytical study was conducted from January 2019 to December 2022 involving two groups of coronary patients (diabetic and nondiabetic) at the rehabilitation centre.

PREVALENCE AND CLINICAL PROFILE OF VENOUS THROMBOEMBOLIC DISEASE IN A TERTIARY CENTER IN DAKAR.

Background: Venous thromboembolic disease (VTE) comprises deep vein thrombosis (DVT) and pulmonary embolism (PE) and ranks third among cardiovascular pathologies. Despite its growing burden in Africa, epidemiological data on VTE in Senegal is scarce. Conclusion: Venous thromboembolic disease is a prevalent and potentially severe condition, especially among relatively young individuals in our setting.

MANAGEMENT DELAYS AND OUTCOMES IN ST-ELEVATION MYOCARDIAL INFARCTION (STEMI) IN THE COVID-19 ERA IN SENEGAL: INSIGHTS FROM A TERTIARY CENTER.

Background: Low-and middle-income countries (LMICs) face many challenges regarding the timely management of STEMI, and the COVID-19 pandemic has impacted our already fragile health systems.

Objectives: To assess the delays in managing STEMI during COVID-19 and evaluate the 6-month mortality rates related to these delays.

Methods: A retrospective cross-sectional study was conducted over two years at a tertiary center in Dakar, Senegal.

Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of .

The study aimed to investigate the chemical composition and antimicrobial and antioxidant activities of the essential oil from dried seeds of . The essential oil was obtained by hydrodistillation and analyzed by GC/FID and GC/MS. The essential oil yield was 1.

A Metabolomic Signature of Ischemic Stroke Showing Acute Oxidative and Energetic Stress.

Metabolomics is a powerful data-driven tool for in-depth biological phenotyping that could help identify the specific metabolic profile of cryptogenic strokes, for which no precise cause has been identified. We performed a targeted quantitative metabolomics study in West African patients who had recently suffered an ischemic stroke, which was either cryptogenic ( = 40) or had a clearly identified cause ( = 39), compared to a healthy control group ( = 40). Four hundred fifty-six metabolites were accurately measured.

Feasibility and safety of integrating mass drug administration for helminth control with seasonal malaria chemoprevention among Senegalese children: a randomized controlled, observer-blind trial.

Background: The overlap in the epidemiology of malaria and helminths has been identified as a potential area to exploit for the development of an integrated control strategy that may help to achieve elimination of malaria and helminths. A randomized, controlled, observer-blind trial was conducted to assess the feasibility and safety of combining mass drug administration (MDA) for schistosomiasis and soil transmitted helminths (STH) with seasonal malaria chemoprevention (SMC) among children living in Senegal.

Methods: Female and male children aged 1-14 years were randomized 1:1:1, to receive Vitamin A and Zinc on Day 0, followed by SMC drugs (sulfadoxine-pyrimethamine and amodiaquine) on Days 1-3 (control group); or praziquantel and Vitamin A on Day 0, followed by SMC drugs on Days 1-3 (treatment group 1); or albendazole and praziquantel on Day 0, followed by SMC drugs on Days 1-3 (treatment group 2).

Prevalence of malaria-helminth co-infections among children living in a setting of high coverage of standard interventions for malaria and helminths: Two population-based studies in Senegal.

Background: Concurrent infections of with Soil Transmitted Helminths (STH) and are still a major public health problem among children living in Sub-Saharan Africa. We conducted two prospective studies among children living in urban and rural settings of Senegal, where control programmes for malaria, STH and schistosomiasis have been sustained, to determine the prevalence of malaria-helminth co-infection.

Methods: We enrolled 910 children aged 1-14 years from Saraya and Diourbel districts of Senegal in June and November 2021, respectively.

Surveillance of Viral Encephalitis in the Context of COVID-19: A One-Year Observational Study among Hospitalized Patients in Dakar, Senegal.

The burden of encephalitis and its associated viral etiology is poorly described in Africa. Moreover, neurological manifestations of COVID-19 are increasingly reported in many countries, but less so in Africa. Our prospective study aimed to characterize the main viral etiologies of patients hospitalized for encephalitis in two hospitals in Dakar.

Spectrum of movement disorders: Experience of a one and half year of existence of the first specialized center in Senegal.

Background: Movement disorders have different prevalence in different regions and they are little studied in Africa.

Objectives: Evaluate the prevalence and determine the spectrum of movement disorders in the first specialized center in Senegal.

Methods: It was a prospective study over on 18 months in adult outpatient clinic.

Profile of Patients with Gallstone Disease in a Sub-Saharan African General Surgery Department: A Retrospective Cohort Study Protocol.

Introduction: Gallstone disease is a disorder characterised by the formation of stones in the biliary tract. It is the most common biliary condition accounting for more than 98% of all gallbladder and biliary tract disorders. In Africa, previous studies have shown a relative rarity of this condition with a prevalence less than 5%; since it is between 2 and 5 times higher in other continents.

Cerebral venous thrombosis in a sub-saharan African country: A preliminary monocentric study of a 70 case series at the neurology department of Fann teaching hospital in Dakar - Senegal.

Introduction: Cerebral venous thrombosis (CVT) are underdiagnosed in sub-saharan Africa where publications are uncommon. Our study aim was to describe the CVT diagnostic and therapeutic features through a senegalese case series.

Patients And Method: A monocentric retrospective and prospective study was conducted at the adult Neurology department of Fann Teaching Hospital in Dakar (Senegal), between January 01, 2013 and April 30, 2020.

[Neuro-Behçet in a Sub-Saharan Africa Country: a Series of Sixteen Patients in Fann Teaching Hospital, Dakar, Senegal].

Neuro-Behçet (NB) African studies are mainly North African, but Sub-Saharan Africa is not to be outdone. Our aim was to describe diagnostic and therapeutic features of NB in a Senegalese series collected in Dakar. This was a descriptive and retrospective study conducted at the Neurology department of Fann Teaching Hospital in Dakar, Senegal.

Acute circulatory failure in two cardiology departments in Dakar: 44 cases.

Introduction: Acute circulatory failure is a life-threatening emergency whose prognosis depends on early management and aetiological diagnosis. The aim of our study was to assess the epidemiological, aetiological, therapeutic and prognostic aspects of acute circulatory failure in two cardiology departments in Dakar.

Methods: This was a longitudinal, multicentre, descriptive study over a period of six months from October 2014 to March 2015.

Crystal structure of ,'-[(ethane-1,2-di-yl)bis-(aza-nediylcarbono-thio-yl)]bis-(benzamide).

The reaction of benzoyl chloride and ethyl-endi-amine in the presence of potassium thio-cyanate yielded a white solid, CHNOS, which consists of two benzoyl-thio-ureido moieties connected by an ethyl-ene chain. The asymmetric unit consists of one half of the mol-ecule, the complete mol-ecule being generated by crystallographic inversion symmetry. Both thio-urea moieties are in a conformation.

Neuromyelitis optica spectrum disorders (NMO-SD) in a Sub-Saharan Africa country: A preliminary study of sixteen Senegalese cases.

Background: Neuromyelitis optica (NMO) is an autoimmune disease of the central nervous system. In Sub-Saharan Africa, publications are rare and deal with isolated cases. Our goal was to analyze the characteristics of NMO spectrum disorders in a Senegalese cohort compiled in Dakar.

Non-compaction of left ventricular myocardium in sub-Saharan African adults.

Background: Non-compaction of the left ventricle (NCLV) is an unclassified cardiomyopathy due to intrauterine arrest of compaction of the loose interwoven meshwork. Only a few studies involving sub-Saharan Africans insmall numbers have been published. The aim of our study was to determine the diagnostic, therapeutic and prognostic aspects as well as the clinical course of NCLV in a black African population.

[Congenital heart disease in adolescents and adults: Management in a general cardiology department in Senegal].

Background: Congenital heart diseases in adults include malformations treated in childhood that decompensate secondarily and those asymptomatic at birth, appear later. This study aims to identify congenital heart diseases in adults in general cardiology department of Senegal and to assess clinical presentations, treatment and outcomes.

Methods: We conducted a cross-sectional and descriptive study based on the records of patients aged at least 16 years and followed for congenital heart disease in the cardiology department of the General Hospital of Grand-Yoff in Dakar between May 2003 and March 2015.

[Comparative Study Of Coronary Artery Disease In Diabetics And Non-Diabetics In The Department Of Cardiology Of Aristide Le Dantec University Hospital].

Unlabelled: The aim of this study was to compare the features of coronary artery disease between diabetic and non-diabetic patients.

Patients And Methods: A case-control study was carried out from 1 May 2013 to 31 July 2015 in the department of cardiology of Aristide le Dantec university hospital. Forty-five diabetic patients and forty-five non-diabetic patients who underwent coronary angiography and / or angioplasty were included.

[Cardiovascular manifestations in systemic lupus erythematosus in Dakar: Descriptive study about 50 cases].

Systemic lupus erythematosus is a non-specific inflammatory disorder of an organ of unknown cause and autoimmune origin. Visceral injuries, including those cardiovascular, determine the prognosis of this disease primarily affecting women. The objectives of this study were to determine the frequency and describe the cardiovascular manifestations in systemic lupus erythematosus in a lupus population of the Dakar region.