Publications by authors named "Gayathri Thashanamoorthi"
Carnosol (CO) and carnosic acid (CA) are pharmaceutically important diterpenes predominantly produced in members of Lamiaceae, Salvia officinalis (garden sage), Salvia fruticosa and Rosmarinus officinalis. Nevertheless, availability of these compounds in plant system is very low. In an effort to improve the in planta content of these diterpenes in garden sage, SmERF6 (Salvia miltiorrhiza Ethylene Responsive Factor 6) transcription factor was expressed heterologously.
View Article and Find Full Text PDFPhanerochaete chrysosporium (Pc), is a prominent lignin-degrading fungus which serves as an important source for lignin-degrading enzymes (LDEs). The present study was focused on a detailed in silico analysis and gene expression patterns of lignin peroxidases (PcLiPs), which is a significant class of LDEs. In spite of extensive research on P.
View Article and Find Full Text PDFArticle Synopsis
- Recombinant biopharmaceuticals, such as antibodies and hormones, are produced using plant molecular pharming, which offers benefits like scalability and reduced contamination risks compared to traditional methods.
- Despite its advantages, plant systems face challenges like non-human post-translational modifications and protein instability that hinder efficient protein expression.
- Artificial intelligence and synthetic biology tools are being integrated to improve protein production in plants by optimizing stability and effectiveness, helping meet the growing demand for therapeutics.