Big data era in healthcare led to the generation of high dimensional datasets like genomic datasets, electronic health records etc. One among the critical issues to be addressed in such datasets is handling incomplete data that may yield misleading results if not handled properly. Imputation is considered to be an effective way when the missing data rate is high.
View Article and Find Full Text PDFNetw Model Anal Health Inform Bioinform
June 2021
Feature selection has gained its importance due to the voluminous nature of the data. Owing to the computational complexity of wrapper approaches, the poor performance of filtering techniques, and the classifier dependency of embedded approaches, hybrid approaches are more commonly used in feature selection. Hybrid approaches use filtering metrics to reduce the computational complexity of wrapper algorithms and are proved to yield better feature subset.
View Article and Find Full Text PDFPatient and public involvement (PPI) is an active partnership between the public and researchers in the research process. In dementia research, PPI ensures that the perspectives of the person with "lived experience" of dementia are considered. To date, in many lower- and middle-income countries (LMIC), where dementia research is still developing, PPI is not well-known nor regularly undertaken.
View Article and Find Full Text PDFObjective: Currently no standardized tools are available in the Indian languages to assess changes in cognition. Our objectives are to culturally adapt the Alzheimer's disease Assessment Scale-Cognitive Subscale (ADAS-Cog) for use in India and to validate the Tamil version in an urban Tamil-speaking older adult population.
Methods: Two panels of key stakeholders and a series of qualitative interviews informed the cultural and linguistic adaptation of the ADAS-Cog-Tamil.
Electronic health records (EHR) are a major source of information in biomedical informatics. Yet, missing values are prominent characteristics of EHR. Prediction on dataset with missing values results in inaccurate inferences.
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