Publications by authors named "Gayathri G"

Article Synopsis
  • Cardiac ochronosis is a rare condition linked to alkaptonuria, characterized by black pigmentation in cardiac structures, discovered in a 60-year-old woman during valve replacement surgery for severe aortic stenosis.
  • Intraoperatively, the presence of a pigmented aortic valve led to the diagnosis of alkaptonuria, prompting a switch from a bioprosthetic to a mechanical valve for better long-term outcomes.
  • Post-surgery, the patient was discharged without complications, with plans for regular follow-up to monitor her valve function and manage her condition's progression.
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The objective of this study is to create and validate a quantitative food frequency questionnaire (FFQ) for the assessment of Vitamin D intake among adults in Indian population. A quantitative FFQ was developed consisting of Vitamin D dietary-rich sources selected from IFCT, 2017. Further, the FFQ was validated against 24-h dietary recall from randomly selected 385 adults, both men and women above 25 years of age.

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Aim To assess the antimicrobial activity of herbal, homeopathic, and conventional dentifrices against oral microorganisms. Methodology Mueller Hilton agar was used to cultivate distinct strains of and , whereas was cultured on a potato dextrose agar medium. Diffusion ratios of 1:5, 1:10, and 1:15 were obtained by diluting 1 gram of each dentifrice (KP Namboodiri, Homeodent, andColgate Strong Teeth) in 4 ml, 9 ml, and 14 ml of distilled water, respectively.

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Background: Use of injectable-platelet rich fibrin (i-PRF) in the field of periodontal regeneration is quite well known due to its efficacy. The study was aimed to evaluate the platelet derived growth factor-BB (PDGF-BB) levels in cases of isolated gingival recession using gingival pedicle split thickness tunnel technique (GPST) and de-epithelialized gingival graft (DGG) with or without coating it with i-PRF.

Methodology: 20 patients exhibiting Miller's class I/II isolated gingival recession were selected for this parallel arm randomized controlled trial.

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High glucose (HG), a hallmark of the tumour microenvironment, is also a biomechanical stressor, as it exerts hyper-osmotic stress (HG-HO), but not much is known regarding how tumour cells mechanoadapt to HG-HO. Therefore, this study aimed to delineate the novel molecular mechanisms by which tumour cells mechanoadapt to HG/HG-HO and whether phytochemical-based interference in these mechanisms can generate tumour-cell-selective vulnerability to cell death. Mannitol and L-glucose were used as hyper-osmotic equivalents of high glucose.

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Background: Post dural puncture headache (PDPH) delays discharge from hospital. We studied the efficacy of sphenopalatine ganglion (SPG) block, a novel technique in management of PDPH using 0.25% Ropivacaine.

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The production of renewable and sustainable biofuels using inevitable wastes is a promising alternative to the alarming depletion of fossil fuels. Significantly, the sustainable biorefinery of lignocellulosic waste, as an alternative fuel source, is a prognosticating approach to tackle many agricultural/forestry residues and offers a circular economy as well as environmental benefits. But, the heterogeneity of lignocellulosic biomass is one of the major bottlenecks in lignocellulosic biorefinery.

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Background: Several bone grafting formulations have been given clinically acceptable outcomes in treating intrabony defects. Platelet rich fibrin (PRF), an autologous platelet concentrate holds potential to be used for regenerative treatment. The purpose of this study was to evaluate clinical and radiographic outcomes in periodontal intrabony defects treated with advanced-PRF block (A PRF + i PRF + nanohydroxyapatite [nHA]) compared to nHA alone.

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The carboxymethylated inulin (CMI) nanoparticles prepared by the salt out method was demonstrated to harvest cellulolytic enzymes (Ez) directly from the clarified fermented broth of Trichoderma harzanium BPGF1. The formation of CMI nanoparticles and entrapment of Ez in CMI was confirmed by scanning electron microscopy and Fourier transform infrared spectroscopy, respectively. A factorial design was developed to maximize enzymes recovery directly from the fermented broth.

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The aim of the our study was to assess the efficacy of autogenous tooth root as a block bone graft in reconstructing the vertical and horizontal dimensions at periodontally hopeless extraction sites both clinically and radiographically. A total of 13 patients having a tooth with periodontally hopeless prognosis and indicated for extraction were included in the study. Following atraumatic extraction, the tooth was processed to create a decoronated cementum-free dentin block which was used to augment the extraction socket.

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Bacterial Cellulose (BC), a valuable biopolymer gaining importance over the past few decades due to its remarkable properties and applications. In this study, crude distillery effluent having a high COD value of 87,433 mg/L was used to produce Bacterial Cellulose under static fermentation by Komagataeibacter saccharivorans, a novel isolated bacterial strain. 1.

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Wernicke's encephalopathy following severe hyperemesis gravidarum is an uncommon clinical entity. We describe a rare manifestation of optic discs swelling in a pregnant woman that has caused a diagnostic dilemma. With high index of suspicion of clinical manifestations and radiological evidences, a clinical diagnosis of Wernicke's encephalopathy was made.

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Zinc oxide nanoparticles (ZnO NPs) are extensively used in a wide variety of commercial products including sunscreens, textiles and paints It is a known fact that ZnO NPs are not stable when dispersed in water, therefore manufacturers use several surface modifying agents to increase the stability of ZnO NPs. In the present study, ZnO NPs were synthesized via chemical co-precipitation with and without the use of surface modifying agents including ethylene glycol (EG), gelatin, polyvinyl alcohol (PVA) and polyvinylpyrrolidone (PVP). Preliminary characterization was done by UV-Visible spectroscopy.

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The incidence of fractures of styloid process, either in isolation or association with mandibular fractures, is rare, and frequently overlooked. When present, they pose clinical dilemma in diagnosis and management. Proper management of styloid fractures is essential, not just to alleviate the patients' symptoms, but also to prevent potential complications like post-traumatic styloid syndrome and injury to adjacent vital structures.

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Piper colubrinum Link., a distant relative of Piper nigrum L., is immune to the oomycete pathogen Phytophthora capsici Leonian that causes 'quick wilt' in cultivated black pepper (P.

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Context: Chronic periodontitis is an inflammatory condition of supporting tissues initiated by organisms in dental plaque. The reactive oxygen species and free radicals mediate connective tissue destruction in periodontitis. In order to counteract the free radical mediated tissue damage, numerous antioxidant mechanisms exist within the host.

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Article Synopsis
  • Various factors, including anatomical, physiological, and pathological aspects, contribute to gingival recession, and existing root coverage procedures often struggle with Class III and IV cases.
  • A newer method called the pedicled buccal fat pad (PBFP) has been developed for treating severe gingival recession and offers advantages due to its vascularized tissue and ability to maintain structure over time.
  • This case report focuses on employing the PBFP technique for root coverage in a Class IV gingival recession at the maxillary right first molar.
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An in vitro antidiabetic activity on α -amylase and α -glucosidase activity of novel 10-chloro-4-(2-chlorophenyl)-12-phenyl-5,6-dihydropyrimido[4,5-a]acridin-2-amines (3a-3f) were evaluated. Structures of the synthesized molecules were studied by FT-IR, (1)H NMR, (13)C NMR, EI-MS, and single crystal X-ray structural analysis data. An in silico molecular docking was performed on synthesized molecules (3a-3f).

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Article Synopsis
  • The study investigated how nonsurgical periodontal treatment affects leptin levels in the saliva of patients with chronic periodontitis.
  • Ninety sites from 30 nonobese chronic periodontitis patients were treated with different methods, including scaling and root planing (SRP) alone or SRP plus tetracycline local drug delivery, and their effects were measured over time.
  • Results showed significant improvements in probing depth and clinical attachment, but the reduction in leptin levels was temporary and not maintained over time, particularly in the group receiving the combined treatment.
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Implant failure can be divided into early (prior to prosthetic treatment) or late (after prosthetic rehabilitation). Early failure is generally due to interference in the healing process after implant placement. Implants undergoing early failure will show progressive bone loss on radiographs during the healing period (4 to 6 weeks).

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Lithium, the first element of Group I in the periodic system, is used to treat bipolar psychiatric disorders. Lithium chloride (LiCl) is a selective inhibitor of glycogen synthase kinase-3β (GSK-3β), a serine/threonine kinase that regulates many cellular processes, in addition to its role in the regulation of glycogen synthase. GSK-3β is emerged as a promising drug target for various neurological diseases, type-2 diabetes, cancer, and inflammation.

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Background: Toothbrush injuries are common in children, and those of impalement and embedded injuries are the more serious.

Case Report: A five-year-old girl presented with a complaint of a swelling affecting the left side of her face and with difficulty in opening her mouth for the previous 15 days. She gave a history of a fall while brushing her teeth.

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