Publications by authors named "Gayathiri Ekambaram"
Colorectal cancer remains a global health challenge, prompting the exploration of natural compounds for treatment. shows promise as a source of activity biomolecules. This study analyzed the dynamics, molecular docking and ADMET properties of the extract, highlighting interaction with inflammatory protein.
View Article and Find Full Text PDFDear Editor, From a scientific perspective, snail mucus, or snail secretion filtrate (SSF), has emerged as a significant discovery in dermatology and regenerative medicine. Several studies on mucus composition have illuminated its features in recent years, yet much remains unexplored. High-quality snail mucus contains adequate levels of active substances (e.
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- Plants can provide therapeutic compounds with fewer side effects than synthetic drugs, prompting research into natural sources for modern pharmaceuticals.
- The study focuses on analyzing the phenolic and flavonoid content of Solanum virginianum seeds, revealing that methanol extracts have higher antioxidant activity and richer compounds compared to other solvent extracts.
- Molecular docking techniques indicated strong binding affinities of key compounds like quercetin and kaempferol with specific amino acids, suggesting the seeds' potential as natural antioxidants and cancer-fighting agents.
Context: The present study aims to investigate the therapeutic potential of phytocompounds derived from Annona reticulata leaves for the treatment of hypertension, utilizing computational methodologies. Gaining a comprehensive understanding of the molecular interactions between neophytadiene and γ-sitosterol holds significant importance in the advancement of innovative therapeutic approaches. This study aims to examine the inhibitory effects of neophytadiene and γ-sitosterol using molecular docking and dynamics simulations.
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- The review examines the environmental impacts of nanotechnology, especially regarding its interactions with plants and their defense mechanisms against nano-pollution stress.
- It emphasizes the role of phytohormones in plant responses to nanomaterials, which underscores the intricate connections within ecosystems.
- The findings suggest that using hyperaccumulator plants in pollution control could lead to sustainable urban environments, but more research is needed on how these nanoparticles affect plant genetics and ecosystems over time.
Article Synopsis
- - The integration of biology and computational science has transformed our understanding of biological systems and paved the way for innovative solutions to global issues like disease and environmental challenges.
- - Genetic engineering and biomolecular simulation are key components of this evolution, offering insights into molecular processes and enabling the development of advanced therapies for genetic disorders and new pharmaceuticals.
- - The ongoing advancements in computational biology are expected to significantly impact fields like cancer treatment and environmental restoration, showcasing its potential to revolutionize our understanding and enhancement of biological systems.
According to worldwide health data, cancer, and inflammatory illnesses are on the rise and are among the most common causes of death. Across the world, these types of health problems are now considered top priorities for government health organizations. Hence, this study aimed to investigate medicinal plants' potential for treating cancer and inflammatory disorders.
View Article and Find Full Text PDFHealthy humans and animals commonly harbor lactic acid bacteria (LAB) on their mucosal surfaces, which are often associated with food fermentation. These microorganisms can produce amphiphilic compounds, known as microbial surface-active agents, that exhibit remarkable emulsifying activity. However, the exact functions of these microbial surfactants within the producer cells remain unclear.
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- Nanotechnology can transform various research fields, utilizing unique nanoparticles that offer features absent in their natural forms.
- Scientists aim to develop safer, genetically improved cyanobacteria for nanoparticle synthesis due to the harmful substances often used in traditional microparticle production.
- The review explores applications, challenges, and future potentials of genetically engineered cyanobacteria in nanotechnology, alongside methods to enhance their industrial applications.
The novel coronavirus 2019 is spreading around the world and causing serious concern. However, there is limited information about novel coronavirus that hinders the design of effective drug. Bioactive compounds are rich source of chemo preventive ingredients.
View Article and Find Full Text PDFIncreased industrialization demand using synthetic dyes in the newspaper, cosmetics, textiles, food, and leather industries. As a consequence, harmful chemicals from dye industries are released into water reservoirs with numerous structural components of synthetic dyes, which are hazardous to the ecosystem, plants and humans. The discharge of synthetic dye into various aquatic environments has a detrimental effect on the balance and integrity of ecological systems.
View Article and Find Full Text PDFPlant-derived antioxidants are a large group of natural products with the capacity to reduce radical-scavenging. Due to their potent therapeutic and preventive actions, these compounds receive a lot of attention from scientists, particularly pharmacologists. The pharmacological activities of the Lam.
View Article and Find Full Text PDFObjectives: Aqueous leaves extracts of and were prepared and effect of the extracts on inhibiting alpha-amylase playing essential roles on converting starch into glucose have been examined using assays.
Methods: Alpha amylase inhibitory assay was used to asses the antidiabetic activity of the extracts. Gas chromatography-mass spectrometry (GC-MS) analysis was performed to identify the volatile molecules of the extracts.