Publications by authors named "Gavin V Thomas"

Objectives: Sensi-IP®OG (SIP-OG) and Sensi-IP®FF (SIP-FF) are soluble bioactive glasses developed to treat dentin hypersensitivity and promote remineralization. Evaluation of their therapeutic potential to reduce dentin hypersensitivity and recover enamel strength was evaluated using standardized in vitro assessments based on simulated use.

Methods: To assess dentin occlusion a visual occlusion methodology was employed.

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Article Synopsis
  • The study compared the effects of two different toothpaste formulations on salivary fluoride and calcium ion concentrations following brushing and rinsing with orange juice or deionized water.
  • The test toothpaste (including cocamidopropyl betaine) showed higher fluoride levels at all time points compared to the comparator, particularly significant from 10 minutes post-brushing.
  • The research highlights that different toothpaste ingredients can affect fluoride retention in the mouth, suggesting that formulation excipients play a crucial role in oral health.
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Objective: This exploratory, randomised, single-blind, crossover, study evaluated fluoride and calcium ion concentrations and pH following use of one of two 1450 ppm fluoride (NaF), 5% w/w KNO dentifrices: (1) test dentifrice (with cocamidopropyl betaine) with an orange juice (OJ) rinse; (2) test dentifrice with a deionized (DI) water rinse or (3) comparator dentifrice (with sodium lauryl sulphate and tetrasodium pyrophosphate) with an OJ rinse.

Design: Eighteen participants used their assigned dentifrice, rinsed with DI water, then expectorate was collected. Sixty min post-brushing, participants rinsed with OJ or DI water then expectorate was collected.

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