Genetic causes and management of male infertility.

Infertility affects approximately 15% of couples. With infertility such a common problem in a generally healthy age group, complete evaluation is needed of both men and women. Infertility work up for men includes a semen analysis, the results of which suggest various supplemental studies, including karyotype.

Heterotopic Ossification Leading to Ureteral Obstruction Resulting in Nephrectomy.

Heterotopic ossification (HO) is the presence of bone in soft tissue where bone normally does not exist. This can be acquired or inherited with the acquired form most often seen with either trauma, spinal cord injury, or central nervous system injury. HO most commonly affects the flexors and abductors of the hip, medial knees, and the shoulders and rarely affects the genitourinary (GU) system.

Eosinophilic Ureteritis in a Child With Ureteropelvic Junction Obstruction and Vesicoureteral Reflux.

Eosinophilic ureteritis is a rare cause of ureteral obstruction, and to date the diagnosis can only be made on pathologic examination. The true underlying cause is not well understood, but there may be some association with eosinophilia, atopy and/or trauma. We present a case of a two-year-old boy with ureteropelvic junction obstruction (UPJO) and ipsilateral vesicoureteral reflux (VUR) found to have eosinophilic ureteritis.

Massively Dilated Lower Pole Ectopic Megaureter with Involuted Lower Pole Renal Moiety and Collecting System: An Exception to the Meyer-Weigert Rule.

Duplicated collecting systems have a predictable draining pattern that is described by the Meyer-Weigert rule. When there are abnormalities associated with duplicating collecting systems, the upper pole moiety drains inferomedially (most commonly associated with obstruction), and the lower pole moiety drains superolaterally (most commonly associated with vesicoureteral reflux). We present a case of an infant with a duplicated collecting system that violates the Meyer-Weigert rule with lower pole megaureter with massive dilation, ectopic insertion, and associated involuted lower pole renal moiety.

Catastrophic Failure of Regenerex Tibial Components: A Case Series.

The aim of this study was to analyze short-term metal failures in well-placed Signature-guided Regenerex (Zimmer Biomet, Warsaw, IN) tibial components in a limited patient series. A retrospective, consecutive, nonrandomized, unblinded study from a limited cohort of young active osteoarthritis patients was conducted. All cases received a Regenerex tibial component which we evaluated for metal failure.