Publications by authors named "Gavin M Hamilton"

Purpose: Improvement in delivery of perioperative care depends on the ability to measure outcomes that can direct meaningful changes in practice. We sought to identify and provide an overview of perioperative quality indicators specific to the practice of anesthesia in noncardiac surgery.

Source: We conducted an umbrella review (a systematic review of systematic reviews) according to Joanna Briggs Institute methodology.

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Purpose: Numerous guideline recommendations for airway and perioperative management during the COVID-19 pandemic have been published. We identified, synthesized, and compared guidelines intended for anesthesiologists.

Source: Member society websites of the World Federation of Societies of Anesthesiologists and the European Society of Anesthesiologists were searched.

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Article Synopsis
  • The study aimed to compare the effectiveness of virtual care with remote automated monitoring (RAM) versus standard care in increasing the number of days adults were able to stay at home after non-elective surgery during the COVID-19 pandemic.
  • Conducted as a multicenter randomized controlled trial in eight Canadian hospitals, 905 adults were divided into two groups: one receiving virtual care with daily monitoring and the other receiving standard post-operative care.
  • The results showed a slight advantage for the virtual care group in terms of days alive at home (29.7 vs. 29.5 days), but the difference was minimal and not statistically significant, indicating no major benefit from the virtual care approach.
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Background: There is need to identify perioperative interventions that decrease chronic opioid use. The authors hypothesized that receipt of a peripheral nerve block would be associated with a lower incidence of persistent postoperative opioid prescription fulfillment.

Methods: This was a retrospective population-based cohort study examining ambulatory shoulder surgery patients in Ontario, Canada.

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Article Synopsis
  • The PVC-RAM trial aims to assess whether virtual care with remote automated monitoring (RAM) improves post-discharge outcomes for patients who have undergone nonelective surgeries during the COVID-19 pandemic.
  • The study involves 900 adults from 8 Canadian hospitals, who are randomly assigned to receive either RAM or standard care, with daily monitoring of vital signs and interaction with nurses over a 30-day period.
  • Results from this trial will help shape better post-surgical care strategies and will be shared through various platforms for broader impact, both during and after the pandemic.
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Background: Preoperative frailty is strongly associated with postoperative complications and mortality. However, the pathways between frailty, postoperative complications, and mortality are poorly described. The authors hypothesized that the occurrence of postoperative complications would mediate a substantial proportion of the total effect of frailty on mortality after elective noncardiac surgery.

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Background: Adverse outcomes and resource use rates are high after hip fracture surgery. Peripheral nerve blocks could improve outcomes through enhanced analgesia and decreased opioid related adverse events. We hypothesized that these benefits would translate into decreased resource use (length of stay [primary outcome] and costs), and better clinical outcomes (pneumonia and mortality).

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Background: Guidelines recommend routine preoperative frailty assessment for older people. However, the degree to which frailty instruments improve predictive accuracy when added to traditional risk factors is poorly described. Our objective was to measure the accuracy gained in predicting outcomes important to older patients when adding the Clinical Frailty Scale (CFS), Fried Phenotype (FP), or Frailty Index (FI) to traditional risk factors.

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Objective: Administrative data systems are used to identify hospital-based patient safety events; few studies evaluate their accuracy. We assessed the accuracy of a new set of patient safety indicators (PSIs; designed to identify in hospital complications).

Study Design: Prospectively defined analysis of registry data (1 April 2010-29 February 2016) in a Canadian hospital network.

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Background: Nerve blocks improve early pain after ambulatory shoulder surgery; impact on postdischarge outcomes is poorly described. Our objective was to measure the association between nerve blocks and health system outcomes after ambulatory shoulder surgery.

Methods: We conducted a population-based cohort study using linked administrative data from 118 hospitals in Ontario, Canada.

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Perioperative intermediate care units (termed surgical special care units) have been widely implemented across health systems because they are believed to improve surveillance and management of high-risk surgical patients. Our objective was to conduct a systematic review to investigate the effects of a 3-level model of perioperative care delivery (ie, ward, surgical special care unit, or intensive care unit) compared to a 2-level model of care (ie, ward, intensive care unit) on postoperative outcomes. Our protocol was registered with PROSPERO, the international prospective register of systematic reviews (CRD42015025155).

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Purpose: Regional anesthesia may have immediate postoperative advantages compared with general anesthesia, but its impact on post-discharge outcomes is poorly described. Our objective was to measure the association between regional anesthesia and outcomes after ambulatory shoulder surgery.

Methods: We conducted a historical cohort study at The Ottawa Hospital.

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Background: Delirium is an acute and reversible geriatric syndrome that represents a decompensation of cerebral function. Delirium is associated with adverse postoperative outcomes, but controversy exists regarding whether delirium is an independent predictor of mortality. Thus, we assessed the association between incident postoperative delirium and mortality in adult noncardiac surgery patients.

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Purpose: To describe the acute and chronic ocular manifestations of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN Overlap syndrome (Overlap syndrome) in children.

Design: Retrospective case series.

Methods: Medical records of children admitted to the Hospital for Sick Children between 2001 and 2011 with SJS, TEN, and Overlap syndrome were reviewed.

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Stevens Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare debilitating mucocutaneuous diseases most commonly associated with severe drug reactions. A review of SJS/TEN cases was undertaken to describe the etiology, patient characteristics, treatment, and outcome in children affected at a large tertiary pediatric hospital. A retrospective chart review examined SJS/TEN cases admitted to a pediatric intensive care unit (PICU) between 2001 and 2011.

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Objective: To examine if different definitions of "recurrent injury" affect the distribution of subsequent injury types and their consequences.

Design: Secondary analysis of prospective injury data.

Setting: Circus shows.

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Previous injury is believed to be a causal risk factor for subsequent injury. Using empirical data on circus artists (n = 1,281 artists) between 2004 and 2008 in Montreal, Canada, as a motivating example, the authors use patient vector plots to demonstrate that a bias away from the null must always occur in the typical analyses cited as evidence (i.e.

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Context: Ice hockey has one of the highest sport participation and injury rates in youth in Canada. Body checking is the predominant mechanism of injury in leagues in which it is permitted.

Objective: To determine if risk of injury and concussion differ for Pee Wee (ages 11-12 years) ice hockey players in a league in which body checking is permitted (Alberta, Canada) vs a league in which body checking is not permitted (Quebec, Canada).

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