Publications by authors named "Gautam Prasad Chaudhary"

The Marburg virus (MARV), belonging to the family, poses a significant global health threat, emphasizing the urgency to develop Marburg virus-like particle (VLP) vaccines for outbreak mitigation. The virus's menacing traits accentuate the need for such vaccines, which can be addressed by VLPs that mimic its structure safely, potentially overcoming past limitations. Early Marburg vaccine endeavors and their challenges are examined in the historical perspectives section, followed by an exploration of VLPs as transformative tools, capable of eliciting immune responses without conventional risks.

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Article Synopsis
  • - Basic Life Support (BLS) is essential care for patients facing life-threatening situations like cardiac arrest, involving trained responders providing crucial interventions before advanced medical help arrives.
  • - The study indicates that a majority of healthcare workers lack sufficient knowledge of BLS techniques, with only 12% demonstrating adequate understanding.
  • - Early intervention and defibrillation are critical for survival, with guidelines suggesting a rapid response can significantly increase chances of survival in cardiac arrest situations.
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Background: This study was designed to evaluate the impact of the COVID-19 pandemic on the learning status of students from different educational boards and universities of Nepal. An online survey was conducted from tenth to twentieth of September 2020 to record the data.

Material And Methods: A self-designed questionnaire link, using "Google form" was sent to the students via social networks.

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Our study was designed to screen the antibacterial potency of leaf and seed extract and to measure their antioxidant effects, total phenol content, total flavonoid content, and total carbohydrate content. Collected samples were extracted by cold maceration. Hexane, ethyl acetate, methanol, and distilled water were used as extraction solvents.

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The purpose of this study was to determine caregivers' knowledge, attitude, and practice (KAP) on the prevention and care of pressure injuries (PIs) in individuals with spinal cord injury. A quantitative cross-sectional study with descriptive correlation design was used to implement a modified semistructured questionnaire using a convenient sampling method. McDonald's standard of learning outcome measurement criteria was used to categorize caregivers' KAP.

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Article Synopsis
  • The study investigated the antibacterial effects and antioxidant properties of extracts from the root bark, leaves, and pericarp of a specific plant, utilizing various solvents for extraction.
  • Results indicated that the methanol extract of root bark demonstrated strong antimicrobial activity against certain bacteria, while the aqueous pericarp extract showed the lowest minimum bactericidal concentration among tested extracts.
  • Additionally, the extracts were found to contain significant levels of total flavonoids, polyphenols, and carbohydrates, with the methanol extract exhibiting the highest antioxidant activity.
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