An optimized approach for annotation of large eukaryotic genomic sequences using genetic algorithm.

Background: Detection of important functional and/or structural elements and identification of their positions in a large eukaryotic genomic sequence are an active research area. Gene is an important functional and structural unit of DNA. The computation of gene prediction is, therefore, very essential for detailed genome annotation.

A review on multiple sequence alignment from the perspective of genetic algorithm.

Sequence alignment is an active research area in the field of bioinformatics. It is also a crucial task as it guides many other tasks like phylogenetic analysis, function, and/or structure prediction of biological macromolecules like DNA, RNA, and Protein. Proteins are the building blocks of every living organism.