Publications by authors named "Gauri N Bhange"
Article Synopsis
- * A study on S9 peptidase from Bacillus subtilis (S9bs) has confirmed its carboxypeptidase activity, which was previously unclear, highlighting key structural elements essential for this function.
- * The research also revealed S9bs forms stable tetramers and identified its molecular arrangement, providing insights that could aid in therapeutic and drug design related to S9 family enzymes.
Acylaminoacyl peptidases (AAPs) play a pivotal role in various pathological conditions and are recognized as potential therapeutic targets. AAPs exhibit a wide range of activities, such as acylated amino acid-dependent aminopeptidase, endopeptidase, and less studied carboxypeptidase activity. We have determined the crystal structure of an AAP from Geobacillus stearothermophilus (S9gs) at 2.
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