Publications by authors named "Gatti J"

Background: Little is known about quality of life, sleep, and mental health in children with moyamoya arteriopathy (MMA). A better understanding of patient-reported outcomes may lead to improved treatment.

Methods: Patients with MMA <26 years old and their caretakers completed validated, age-appropriate questionnaires including the Pediatric Quality of Life (PedsQL) Inventory and Patient-Reported Outcomes Measurement Information System (PROMIS) measuring health-related quality of life, sleep, anxiety, depression, and overall health.

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Background: Exposed cranial bone can present a considerable challenge to the reconstructive surgeon. Removal of the outer cortex of exposed skull bone has proven effective in the management of complex scalp wounds for which traditional reconstruction efforts were limited.

Objective: To demonstrate a simplified approach for management of scalp wounds with exposed skull.

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Article Synopsis
  • - Clean intermittent catheterization (CIC) is essential for managing urinary issues in children with neurogenic lower urinary tract dysfunction (NLUTD) due to conditions like spinal dysraphism and spinal cord injury, but adherence to this treatment is often low (18%-66%), leading to serious complications like UTIs and renal insufficiency.
  • - This proposed study will investigate caregiver adherence to CIC protocols and the factors affecting it, using a mixed methods approach to gather both qualitative and quantitative data from 60 adult caregivers of children diagnosed with spinal dysraphism or spinal cord injury.
  • - The analysis will include assessing adherence rates through established questionnaires and conducting thematic analysis on interviews to better understand caregiver experiences, with efforts made to ethically disseminate the findings
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  • The study aimed to assess the effectiveness of exam under anesthesia with vaginoscopy (EUA-V) for patients with congenital adrenal hyperplasia (CAH) after undergoing vaginoplasty.
  • A retrospective review involved 26 patients, with findings indicating that EUA-Vs were performed mainly for routine evaluation, identifying complications like stenosis in about 25% of cases.
  • The results suggest that EUA-V might be a valuable tool for monitoring postoperative outcomes in CAH patients following vaginoplasty, highlighting the need for careful follow-up care.
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Recent years have witnessed heightened scrutiny of the non-target sublethal effects of pesticides on behavioural and physiological traits of insects. Traditionally, attention has focused on investigating pesticides' primary modes of action, often overlooking the potential secondary mechanisms. This review brings forth the nuanced impacts of sublethal pesticide exposure on the immune system of target and non-target insect species.

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After separation on gel zymography, hemolymph displays gelatinase and caseinase bands of varying sizes, ranging from over 140 to 25 kDa. Qualitative and quantitative variations in these bands were observed during larval development and between different strains and Drosophila species. The activities of these Drosophila hemolymph gelatinase and caseinase were strongly inhibited by serine protease inhibitors, but not by EDTA.

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Background: Children with moyamoya are at high risk for incident and recurrent stroke. Transcranial Doppler (TCD) ultrasound is an attractive option to screen high-risk populations for moyamoya and to provide stroke risk stratification information due to its safety and cost-effectiveness. We used TCD to evaluate cerebral blood flow velocities in children with presurgical moyamoya and to determine if velocities differ between children with stable and unstable disease.

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Objectives: Surgical revascularization for moyamoya arteriopathy decreases long-term stroke risk but carries a risk of perioperative ischemic complications. We aimed to evaluate modifiable stroke risk factors in children undergoing surgical revascularization for moyamoya.

Materials And Methods: In this exploratory, single-center, retrospective cohort study, medical records of pediatric patients undergoing surgical revascularization for moyamoya arteriopathy at our center between 2003 and 2021 were reviewed.

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  • Dissection of cadavers is important for medical education, but many U.S. institutions use unclaimed bodies, raising ethical concerns; the study investigates medical students' attitudes on this practice.
  • A survey of 212 medical students revealed that while 80% view cadaver dissection as essential, only 30% consider the dissection of unclaimed bodies ethical, with 47% deeming it unethical.
  • Students feel significantly more comfortable with self-donated bodies compared to unclaimed bodies, and comfort levels were influenced by factors like gender and class cohort.
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Background: Defects of the central ear after skin cancer removal remain a common problem for the reconstructive surgeon. The experience with a one-stage, postauricular, skin-island flap passed through the cartilage to reconstruct ear defects is reported.

Methods: Patients with an intact ear helix and an anterior full-thickness defect (cartilage defects included) were reconstructed with a skin-island flap based on posterior subcutaneous tissue deep to the flap base.

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Fixed-timed artificial insemination (FTAI) protocols for beef cattle in South America are primarily based on estradiol esters and intravaginal progesterone-releasing devices (IVPD). The objective of this study was to determine the optimal gonadotropin-releasing hormone (GnRH)-based protocol as an alternative to the use of estrogen-based protocols in grazing suckling beef cows. All cows received an IVPD on the day of protocol initiation and prostaglandin F (PG) plus equine chorionic gonadotropin (eCG) treatments at the time of IVPD removal.

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Behavioural avoidance has obvious benefits for animals facing environmental stressors such as pathogen-contaminated foods. Most current bioinsecticides are based on the environmental and opportunistic bacterium () that kills targeted insect pests upon ingestion. While food and oviposition avoidance of bioinsecticide by targeted insect species was reported, this remained to be addressed in non-target organisms, especially those affected by chronic exposure to bioinsecticide such as species.

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Background: Children with moyamoya arteriopathy are at high risk for stroke and seizures. Risk factors for seizures and the impact of seizures on neurological outcomes in children with moyamoya are unknown.

Methods: This is a single-center retrospective cohort study of children with moyamoya evaluated between 2003 and 2021.

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Upper blepharoplasty is a common aesthetic surgery procedure which is frequently performed wide awake, under local anesthesia. However, advancements concerning the patients' perception during and after the procedure are still needed. This study aimed to evaluate the efficacy of a new method for local anesthetic infiltration in the upper eyelid comparing it to the traditional needle injections.

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Introduction: Anderson-Hynes pyeloplasty is the technique of choice for the treatment of pyeloureteral junction obstruction (PUJO) with an excellent success rate. Minimally invasive surgery has become the standard of care for the management of PUJO in children. Although it has been comparable to the open approach at all levels, its diffusion or employment in younger children has not been widely adopted.

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Lip-Shortening Surgery.

Plast Reconstr Surg

October 2023

Background: Many changes are associated with the aging face. Upper lip lengthening with atrophy, lip thinning, and diminution of the lip margin are commonly seen.

Methods: Lip-shortening surgery over a 32-year period by a single surgeon is reviewed.

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Article Synopsis
  • The study aimed to address the management of gynecologic concerns in female patients aged 10-25 with anorectal malformations (ARMs), focusing on those with Mullerian anomalies.
  • A retrospective review included 12 patients with various gynecologic issues, such as dysmenorrhea and obstructed Mullerian anomalies, with significant time spent gathering input from patients and healthcare providers before intervention.
  • The findings emphasize the need for comprehensive follow-ups that consider psychological and reproductive health, advocating for patient involvement and psychological consultations prior to surgical procedures.
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Introduction: Moyamoya arteriopathy is a severe, progressive cerebral arteriopathy that places affected children at high risk for stroke. Moyamoya has been associated with a range of neuropsychological deficits in adults, but data on many cognitive domains remain limited in the pediatric population and little is known about the neuropsychological profile of children with syndromic moyamoya.

Methods: This is a single-center, retrospective cohort study of children with moyamoya arteriopathy followed at our center who underwent neuropsychological testing between 2003 and 2021.

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Purpose: The Anderson-Hynes technique has been the treatment of choice for primary ureteropelvic junction obstruction in children. Laparoscopic approach has shown similar outcomes to open, with advantages of shorter hospital stay and less pain. We reviewed the experience of 11 geographically diverse, tertiary pediatric urology institutions focusing on the outcomes and complications of laparoscopic pyeloplasty.

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Purpose: Patients with neurogenic bladder (NB) often perform clean intermittent catheterization (CIC) and are predisposed to bladder colonization. Antibiotics are not routinely indicated in those with asymptomatic bacteriuria (ASB). The original purpose of this study was to compare patients that received antibiotics for ASB and those that did not.

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Patients with moyamoya arteriopathy are at high risk for developing ischemic stroke in the perioperative period. We sought to evaluate whether preoperative clinical and neuroimaging biomarkers are associated with postoperative stroke and transient ischemic attack in children with moyamoya following revascularization surgery. We performed a retrospective chart review of pediatric patients who underwent revascularization surgery for moyamoya in the last 15 years.

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Article Synopsis
  • Cerebral small vessel disease (SVD) is a common problem in older people that can lead to stroke and dementia.*
  • The disease CADASIL, which is inherited, happens due to changes in a protein called NOTCH3 that affect its structure.*
  • Researchers found that these changes lead to more bad connections in the protein and make it less stable, which could be harmful for the brain.*
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Purpose: Malone antegrade continence enemas (MACE) provide a conduit in which the patient can achieve improved continence, be clean of stool, and gain independence in maintaining bowel function. The Mini-ACE® is a low-profile balloon button that is used to facilitate the administration of antegrade enemas. We sought to describe our practice and short-term outcomes.

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The Drosophila endoparasitoid wasps Leptopilina boulardi and L. heterotoma (Hymenoptera: Cynipidae) are pro-ovigenic species, i.e.

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