Facet-occiput slope angle: A novel predictor of cage placement feasibility during surgery in basilar invagination patients.

Background And Aim: Direct posterior reduction and manipulation of the C joints, accompanied by placement of spacers, is the state-of-the-art technique for treating basilar invagination (BI) and atlantoaxial dislocation (AAD). The hindrance of occiput to reaching up to the true atlantoaxial facets (AAF) during the surgery remains challenging for cage placement. The aim of this study was to explore an objective and precise method of measuring the effect of the hindrance of occiput to reaching up to the true AAF and cage placement during surgery.

Tumor microenvironment characterization in cervical cancer identifies prognostic relevant gene signatures.

Objective: The aim of this study is to systematically analyze the transcriptional sequencing data of cervical cancer (CC) to find an Tumor microenvironment (TME) prognostic marker to predict the survival of CC patients.

Methods: The expression profiles and clinical follow-up information of CC were downloaded from the TCGA and GEO. The RNA-seq data of TCGA-CESC samples were used for CIBERSORT analysis to evaluate the penetration pattern of TME in 285 patients, and construct TMEscore.

Cervical instability in cervical spondylosis patients : Significance of the radiographic index method for evaluation.

Background: Cervical spondylosis is one of the most common causes of cervical instability. Various methods are used for measuring cervical instability on X‑ray films. The purpose of this study was to assess the application of the radiographic index method to analyze the radiographic features of cervical spondylosis instability.