[Effect of puberty on the development of diabetic microangiopathy].

Fluorescein angiography was used to follow the development of retinal microangiopathy at the time of puberty in 34 children with type I diabetes. When the results were compared with those for the control children who had suffered from the disease for a similar length of time, it was concluded that (in contrast with certain literature data) the process of sexual maturation does not essentially influence the development of retinal microangiopathy if the diabetes is maintained under good control for a long-lasting period. Appreciable roles in the rapid progression that is frequently observed in early adulthood are attributed to the sudden changes in the previously systematic living conditions (school, family, etc.

Recessive genetic deregulation abrogates c-myc suppression by interferon and is implicated in oncogenesis.

In a previous study we demonstrated that many hematopoietic tumor cells are resistant to the inhibitory effects that interferon exerts on c-myc mRNA expression without losing other receptor-mediated intracellular responses (M. Einat, D. Resnitzky, and A.

[On the appearance of the eye fundus in polycythaemia vera (author's transl)].

The authors discuss the ophthalmological and physical symptoms of polycythaemia vera. They established that the severity of the changes in the fundus depend in the same way on the red cell count and the duration of the illness. In an attempt to find the cause of the complications communicated in the literature in arterial spasm and venous stasis, the authors compared statistically the less severe cases and those cases with arterial stenosis which can also be found in uncomplicated cases, and the cases with venous stasis.