Publications by authors named "Gaston P Rizzo"
Article Synopsis
- * The study evaluated the effects of poly(allylamine hydrochloride) (PAH)-based nanoparticles on antigen-presenting cells and found that they boosted important immune responses, increasing the expression of CD86 and MHCII and promoting the production of cytokines IL-1β and IL-18.
- * Results indicated that systemic administration of Np-OVA led to a strong immune response in mice, characterized by increased specific antibodies and activation of T-helper cells, suggesting potential for new vaccine development against various diseases.
The intestinal mucosa is lined by epithelial cells, which are key cells to sustain gut homeostasis. Food allergy is an immune-mediated adverse reaction to food, likely due to defective regulatory circuits. is a non-pathogenic bacterium with immunomodulatory properties.
View Article and Find Full Text PDFBackground: IgE-mediated food allergy remains a significant and growing worldwide problem. Sublingual immunotherapy (SLIT) shows an excellent safety profile for food allergy, but the clinical efficacy needs to be improved. This study assessed the effects of the Toll-like receptor 4 agonist outer membrane protein (Omp) 16 from Brucella abortus combined with cow´s milk proteins (CMP) through the sublingual route to modulate cow's milk allergy in an experimental model.
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