The review compares different porcine models of metabolic syndrome, emphasizing their importance for understanding the disease and developing treatments.
It highlights the challenges posed by metabolic syndrome and the need for better models to fill knowledge gaps in its pathogenesis and therapeutic strategies.
Among the models evaluated, the Ossabaw miniature swine is noted as a promising option due to its resemblance to human metabolic syndrome and associated comorbidities, but further advancements are needed for greater accuracy in replicating secondary effects.