Publications by authors named "Gasior Z"
Background: Current guidelines do not recommend β-blockers in pulmonary arterial hypertension (PAH) unless indicated by comorbidities. However, the evidence regarding the role of β-blockers in PAH is contradictory.
Research Question: What are the effects of β-blockers on clinical outcomes in patients newly diagnosed with PAH, and how do these outcomes differ based on the presence of cardiovascular comorbidities that are standard indications for β-blocker use?
Study Design And Methods: We analyzed data from 806 patients newly diagnosed with PAH enrolled prospectively in the Database of Pulmonary Hypertension in the Polish Population (BNP-PL).
The need to conduct research on anxiety and depression in patients with coronary artery disease in connection with factors such as gender or implemented tertiary prevention is very important for drawing practical conclusions and, consequently, implementing new recommendations and procedures. The aim of the study was to attempt to answer the question whether gender and the number of comorbidities, as well as the application of tertiary prevention principles, play a role in the severity of anxiety and depression in the studied group of patients with coronary artery disease. The study involved 765 patients from 11 Polish cardiology centers.
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- * Results showed men, younger individuals, and those who maintained a healthy weight and followed medical advice had better quality of life, while many patients still struggled with physical activity recommendations despite dietary improvements.
- * The findings highlighted a need for improved patient education on the importance of adhering to lifestyle changes for better health outcomes and quality of life following heart incidents.
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- The study aimed to compare three diagnostic methods for heart failure with preserved ejection fraction (HFpEF): diastolic stress echocardiography (DSE), the H₂FPEF score, and the HFA-PEFF algorithm.
- It involved 80 patients suspected of having HFpEF, where various scores and biomarker concentrations were measured prior to DSE.
- Results indicated that the HFA-PEFF algorithm identified more cases of HFpEF than DSE, while both of the scoring methods had limited ability to accurately predict positive DSE results, highlighting the need for improved diagnostic tools.
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- Transthoracic echocardiography (TTE) and cardiovascular magnetic resonance (CMR) are key imaging techniques used to assess heart conditions, but they can yield different results, particularly for left-ventricular (LV) remodeling.
- In a study of 202 patients scheduled for elective cardiovascular diagnoses, TTE consistently showed higher LV mass index (LVMi) and lower end-diastolic volumes compared to CMR, leading to potential discrepancies in treatment decisions.
- The study suggests that CMR should be more commonly used in clinical practice for patients with significant LV remodeling since it may provide more accurate information that influences clinical management.
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- The study aimed to evaluate classic risk factors in patients with heart failure and their correlation with the activity of specific genes.
- It involved 150 patients, including those with heart failure due to coronary artery disease, with the most common risk factors being hypertension and obesity.
- Higher gene activity was linked to risk factors like obesity and smoking, indicating their roles in the progression of heart failure during myocardial ischemia, emphasizing the need for education on healthy lifestyle choices.
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- Transvenous temporary cardiac pacing (TTCP) is critical for patients experiencing bradycardia, with this study focusing on comparing those with myocardial infarction (MI) to those with other causes.
- The study analyzed 244 cases, finding that MI patients tended to be younger and had a higher rate of hypertension and heart failure, but did not have a higher rate of TTCP complications.
- In-hospital death rates were significantly higher for MI patients, indicating that the severity of MI, rather than the procedure itself, is linked to increased mortality risk.
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- Recent research shows that changes in glucose and lipid metabolism in idiopathic pulmonary arterial hypertension (IPAH) relate to the severity of the disease and survival rates, but the effects of diabetes mellitus (DM) on IPAH prognosis are less understood.
- The study analyzed data from a national registry of Polish patients with IPAH, focusing on information collected from March 2018 to August 2020, and assessed all-cause mortality over a 30-month period while controlling for factors like age and body mass index (BMI).
- The results revealed that 25.6% of the 532 patients had DM, which was linked to more severe symptoms and higher mortality rates in IPAH compared to those without DM, indicating that patients
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- After an acute myocardial infarction (AMI), patients face a high risk of cardiovascular issues, making effective management of cholesterol levels essential.
- A study examined the effectiveness of the Managed Care for Acute Myocardial Infarction Survivors (MACAMIS) program in helping AMI patients achieve cholesterol treatment goals over a year.
- Results showed that while most patients received high-intensity statin therapy and there were improvements in combined treatment approaches, only 20.4% met the desired LDL-C targets, indicating a continued need for better lipid management.*
Background: Protective vaccinations are one of the basic means of infectious disease prevention. The aim of the study was to assess the implementation of compulsory and additional protective vaccinations among adult Poles, their knowledge about the purpose of introducing a vaccination schedule and adverse events following immunization. Opinions about and support for anti-vaccination movements were also examined.
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- The Managed Care in Acute Myocardial Infarction (MC-AMI) program in Poland aims to enhance care for AMI patients and improve long-term outcomes.
- A study comparing 24-month mortality and major cardiovascular events (MACE) between patients treated during the MC-AMI era and a similar group treated before showed significant benefits for those under MC-AMI care.
- Results indicated a 30% reduction in all-cause mortality and a 14% decrease in MACE, with the most significant improvement seen in patients actively participating in the MC-AMI program.
Introduction: Adiposity has a few phenotypes associated with various levels of risk for diabetes mellitus (DM), but their exact predictive value is not well understood.
Objectives: We aimed to assess the predictive value of anthropometric parameters, vascular ultrasound indexes, and fat depots for long‑term cardiometabolic risk.
Patients And Methods: A total of 150 patients with chronic coronary syndrome (CCS) scheduled for elective coronary angiography were enrolled and a comprehensive clinical and ultrasound assessment of adiposity was performed (2012-2013).
We aimed to evaluate the clinical course and impact of the SARS-CoV-2 pandemic on the rate of diagnosis and therapy in the complete Polish population of patients (pts) with pulmonary arterial hypertension (PAH-1134) and CTEPH (570 pts) treated within the National Health Fund program and reported in the national BNP-PL database. Updated records of 1704 BNP-PL pts collected between March and December 2020 were analyzed with regard to incidence, clinical course and mortality associated with COVID-19. Clinical characteristics of the infected pts and COVID-19 decedents were analyzed.
View Article and Find Full Text PDFA patient's compliance to a physician's lifestyle information is essential in chronic coronary syndrome (CCS) patients. We assessed potential characteristics associated with a patient's recollection of physician information and lifestyle changes. This study recruited and interviewed patients (aged ≤ 80 years) 6-18 months after hospitalization due to acute coronary syndrome or elective myocardial revascularization.
View Article and Find Full Text PDFIntroduction: A potentially new marker of cardiovascular diseases - proadrenomedullin is the precursor of adrenomedullin, which is a multifunctional peptide hormone, produced in most of the tissues in response to cellular stress, ischemia, and hypoxia.
Methods: Ninety-three people, aged 51-79 years, were included in the study. Exclusion criteria were severe or corrected valvular disease, acute coronary syndrome, age ≥ 80 years, glomerular filtration rate < 45 ml/min, active infectious diseases, and cancer.
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- Diastolic dysfunction (DD) is hard to diagnose, especially in patients with preserved left ventricular ejection fraction (LVEF) but who show heart failure symptoms.
- The study evaluated the effectiveness of diastolic stress echocardiography (DSE) and specific heart failure biomarkers in diagnosing DD in these patients, involving 80 participants with various health backgrounds.
- Results showed that DSE identified DD in 21% of patients, and certain factors like age and resting NT-proBNP levels helped predict positive DSE outcomes, enhancing the overall diagnostic capabilities of echocardiography.
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- Despite advancements in treating acute myocardial infarction (AMI), post-discharge death rates remain high, particularly in patients with heart failure (HF) post-MI, with only about half surviving four years.
- The study analyzed the effects of managed care after AMI (MC-AMI) on survival rates in patients with existing HF, involving 7228 patients in Poland, with MC-AMI participants showing significantly lower mortality rates.
- Results indicated that MC-AMI participation led to reduced strokes, fewer hospitalizations for HF, and overall better survival rates within the first year, establishing it as a key factor for improving outcomes in these patients.
Introduction: Adherence to health‑promoting behaviors intended to mitigate modifiable risk factors plays an important role in secondary cardiovascular prevention.
Objectives: We aimed to evaluate sex differences in the prevalence and control of risk factors in patients with coronary heart disease (CHD).
Patients And Methods: The study included 1236 patients who experienced acute coronary syndrome or coronary revascularization within the last 6 to 24 months.