Experimental confirmation of the promising selective use of "green" laser radiation for photothermolysis of hemoglobin-containing tissues.

To date, the problem of treating pathological subepithelial capillary structures, in particular, capillary angiodysplasia of the skin, remains. One of the promising methods for its elimination is photothermolysis by laser radiation of the yellow-green spectral range due to the selective absorption of blood by hemoglobin in blood vessels and, subsequently, their sclerosis and regression. In experimental work in vitro on model objects, chilled liver and skin samples from minipigs of the Svetlogorsk population, a comparison was made based on morphological studies of the results of the green laser radiation effect with a wavelength of 525 nm on these objects.

[Galactin-3: diagnostic and prognostic value in patients with chronic heart failure].

Now there is a relevant development of the new biomarkers capable to serve as the instrument of early diagnostics of a disease for the purpose of selection of a pharmacotherapy and further monitoring of its efficiency. Galektin-3 is the atypical representative of the family of galektin. Its participation in fibrosis, remodeling of heart, the immunologic answer and inflammatory reactions are shown.

THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION.

Objective: to determine the effectiveness of combined treatment with hepatoprotectors and antioxidant a complexpreparation of vitamins A and E (I) in patients with non-alcoholic steatohepatitis (NASH) who suffered from theChornobyl NPP accident based on the results of evaluation of metabolic changes.

Materials And Methods: The state of the hepatobiliary system of 72 patients with NASH suffered as a result of theChornobyl accident was studied based on the results of the biochemical analysis of blood, indicators characterizingthe processes of oxidative modification of macromolecules and the state of the antioxidant system (AOS), as well asstructural changes in the liver according to ultrasound investigations in the course of the examination before andafter treatment.

Results: The treatment of NASH with hepatoprotectors and antioxidant I in the sufferers of the Chornobyl accidentincreased the level of antioxidant defense products (catalase and superoxide dismutase) with the normalization ofthe integral index of the AOS, and a significant decrease in the number of patients with reduced AOS status (from42.

[An assessment of cerebrolysin effect on BDNF level in patients with post stroke aphasia depending on carbohydrate metabolism disorders].

Aim: We carried out an open randomized controlled study to explore the changes in the rate of speech recovery and BDNF concentrations in patients with left-hemisphere stroke and carbohydrate metabolism disorders (diabetes mellitus type2 or prediabetes) who received cerebrolysin.

Material And Methods: A study included 60 inpatients of the Center of Speech Pathology and Neurorehabilitation. Neuropsychological examination was performed at baseline and after the treatment was completed.

Clinical importance of the nonalcoholic fatty liver disease: a review.

Literature data analysis summarizing features and peculiarities of clinical presentation, pathways and complications of the nonalcoholic fatty liver disease is presented. The key role of insulin resistance, lipid and carbohydrate metabolic disorders, lipid peroxidation and abnormal antioxidant defense system is described. Clinical importance of non-alcoholic fatty liver disease is essential because of a widespread comorbidity and imbalance in the key regulatory body systems.

[Frequency dynamics of stomach and duodenum ulcer found in liquidators of consequence of Chernobyl accident (according to the data of long-term observation)].

The authors have studied the frequency dynamics of stomach and duodenum ulcer occurrence revealed in liquidators of consequence of Chernobyl accident (1986-1987) after long-term medical observation with age and radiation absorbed dose variations. According to the findings, duodenum ulcer incidence prevails over stomach ulcer in all scale of age. The connection between the frequency dynamics of duodenum ulcer and age of the patients wasn't found.

[Changes in portal and hepatic blood flow in patients with chronic kidney failure as shown by Doppler ultrasonography].

45 patients with chronic renal failure (CRF) were examined for blood flow in the portal vein and hepatic artery using impulse dopplerography. In the hepatic artery there was lowering of maximal systolic blood flow, end diastolic blood flow, elevated pulsative index and index of resistance. These changes appeared at early stages of CRF and progressed with its progression.