Challenges in data-driven geospatial modeling for environmental research and practice.

Machine learning-based geospatial applications offer unique opportunities for environmental monitoring due to domains and scales adaptability and computational efficiency. However, the specificity of environmental data introduces biases in straightforward implementations. We identify a streamlined pipeline to enhance model accuracy, addressing issues like imbalanced data, spatial autocorrelation, prediction errors, and the nuances of model generalization and uncertainty estimation.

[Bilateral stenting for malignant tracheal and bronchial stenosis].

Malignant lesions of tracheal bifurcation usually lead to respiratory failure and risk of mortality. Airway stenting is the only minimally invasive method for these patients. The authors present a patient with T4N3M0 left-sided lung cancer (inoperable stage IIIc) complicated by respiratory failure due to tracheal bifurcation obstruction.

[Endoscopic vacuum therapy in minimally invasive treatment of esophageal perforations].

Objective: To compare the results of endoscopic vacuum therapy (EVT) and open surgery for esophageal perforations.

Material And Methods: The study included 60 patients with esophageal perforations between 2010 and 2022. The main group included 29 patients who underwent minimally invasive treatment with EVT, the control group - 31 patients after open surgical interventions.

The Role of Hydrogen Sulfide in the Localization and Expression of p53 and Cell Death in the Nervous Tissue in Traumatic Brain Injury and Axotomy.

Traumatic brain injury (TBI) is one of the leading causes of disability and death worldwide. It is characterized by various molecular-cellular events, with the main ones being apoptosis and damage to axons. To date, there are no clinically effective neuroprotective drugs.

The Role of Hydrogen Sulfide in Regulation of Cell Death following Neurotrauma and Related Neurodegenerative and Psychiatric Diseases.

Injuries of the central (CNS) and peripheral nervous system (PNS) are a serious problem of the modern healthcare system. The situation is complicated by the lack of clinically effective neuroprotective drugs that can protect damaged neurons and glial cells from death. In addition, people who have undergone neurotrauma often develop mental disorders and neurodegenerative diseases that worsen the quality of life up to severe disability and death.

The Role of Gasotransmitter-Dependent Signaling Mechanisms in Apoptotic Cell Death in Cardiovascular, Rheumatic, Kidney, and Neurodegenerative Diseases and Mental Disorders.

Cardiovascular, rheumatic, kidney, and neurodegenerative diseases and mental disorders are a common cause of deterioration in the quality of life up to severe disability and death worldwide. Many pathological conditions, including this group of diseases, are based on increased cell death through apoptosis. It is known that this process is associated with signaling pathways controlled by a group of gaseous signaling molecules called gasotransmitters.

Bayesian Aggregation Improves Traditional Single-Image Crop Classification Approaches.

Accurate information about growing crops allows for regulating the internal stocks of agricultural products and drawing strategies for negotiating agricultural commodities on financial markets. Machine learning methods are widely implemented for crop type recognition and classification based on satellite images. However, field classification is complicated by class imbalance and aggregation of pixel-wise into field-wise forecasting.

Large-scale forecasting of Heracleum sosnowskyi habitat suitability under the climate change on publicly available data.

This research aims to establish the possible habitat suitability of Heracleum sosnowskyi (HS), one of the most aggressive invasive plants, in current and future climate conditions across the territory of the European part of Russia. We utilised a species distribution modelling framework using publicly available data of plant occurrence collected in citizen science projects (CSP). Climatic variables and soil characteristics were considered to follow possible dependencies with environmental factors.

Inhaled [D-Ala]-Dynorphin 1-6 Prevents Hyperacetylation and Release of High Mobility Group Box 1 in a Mouse Model of Acute Lung Injury.

COVID-19 is a respiratory infection caused by the SARS-CoV-2 virus that can rapidly escalate to life-threatening pneumonia and acute respiratory distress syndrome (ARDS). Recently, extracellular high mobility group box 1 (HMGB1) has been identified as an essential component of cytokine storms that occur with COVID-19; HMGB1 levels correlate significantly with disease severity. Thus, the modulation of HMGB1 release may be vital for treating COVID-19.

Millisecond dynamics of deformation bands during discontinuous creep in an AlMg polycrystal.

Formation of bands of macroscopic strain localization during staircase creep in an AlMg polycrystal is studied by the acoustic emission (AE) technique and high-speed video recording with an image acquisition rate up to 50 000 frames per second. The simultaneous measurements by two methods allow us to distinguish different types of embryo deformation bands and concomitant AE signals, and to establish correlations between the band evolution and the acoustic response. It is found that the fastest stages of band formation, associated with its emergence to the surface and subsequent accelerated expansion, generate complex AE bursts in the frequency band ∼0.

[Spontaneous diffuse chylous peritonitis during pregnancy].

Spontaneous chylous peritonitis during pregnancy is a rare disease. Only a few publications are currently devoted to this problem. The authors reported successful treatment of a patient with spontaneous chylous peritonitis in the first trimester of pregnancy.

THE ROLE OF MYOSTATIN AND PROTEIN KINASE-B IN THE DEVELOPMENT OF PROTEIN-ENERGY DEFICIENCY IN PATIENTS WITH END-STAGE RENAL DISEASE ON HEMODIALYSIS.

In patients with chronic renal failure receiving hemodialysis, the development of protein-energy wasting (PEW) has a significant impact on the quality and duration of life. Myostatin (MSTN) and protein kinase-β (AKT) play an important role in this process. The aim of our study was to assess the contribution of these molecular markers of muscle metabolism to the development of PEW in patients with chronic kidney disease stage 5D (CKD5D).

FEATURES OF THE UBIQUITIN-PROTEASOME SYSTEM IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE 5D.

The aim of the study was to assess the activity of the ubiquitin-proteasome system in patients with chronic kidney disease stage 5D (CKD5D) and its relationship with clinical and laboratory parameters. We examined 80 patients with CKD5D on hemodialysis (HD). The mean age was 51.

[Optimal time of surgery for acute adhesive small bowel obstruction].

Aim: To define optimal terms of surgery for acute adhesive non-strangulatory small bowel obstruction.

Material And Methods: The analysis included 703 publications from e-LIBRARI.RU (342 works) and NCBI (361 works) databases for acute adhesive intestinal obstruction.

CLINICAL FEATURES OF THERAPY OF ANEMIA AND THE SIGNIFICANCE OF ITS FLUCTUATION IN THE DEVELOPMENT OF ANEMIA IN DIALYSIS PATIENTS.

The aim of our study was to examine the features of therapy of anemia, and the influence of fluctuation in dose of antianemic drugs on hemoglobin levels in dialysis patients. The study included 100 patients with chronic kidney disease stage 5D receiving hemodialysis, mean age was 53,4±15,8 years. The clinical and anamnestic data were studied and laboratory tests were performed in all patients.

[The causes of recurrent ulcerative gastroduodenal bleeding].

Aim: To explore microcirculatory changes within the first 48 hours after admission, to compare them with clinical manifestations of bleeding and to define the dependence of recurrent bleeding from the therapy.

Material And Methods: The study included 108 patients with ulcerative gastroduodenal bleeding who were treated at the Clinical Hospital #71 for the period 2012-2014. There were 80 (74.

[Technology of minimally invasive cryodestruction of recurrent tumors].

In oncology practice it has been introduced minimally invasive technology of puncture access for cryodestruction of tumors of various sites as well as obtained positive clinical results.

[Dopamine receptor agonists: new forms and new possibilities in the treatment of Parkinson's disease].

Main mechanisms of action of dopamine receptor agonists, efficacy of their use according to the results of earlier clinical trials and possible side-effects are discussed. The authors present their experience of prescription of rotigotine transdermal system in an open study of 30 patients with Parkinson's disease. The duration of the study was 8 weeks.

[Рformation of algorithms to determine the severity of endotoxemia in peritonitis].

We have analyzed the results of treatment of 110 patients admitted to a clinic with diagnosed acute peritonitis for the period from 2010 to 2014. Patients were divided into three groups according to the classification of B. Savchuk.

[The role of lipid peroxidation in pathogenesis of hepatic enzymatic dysfunction during peritoneal intoxication].

We have investigated the role of lipid per oxidation in pathogenesis of hepatic enzymatic dysfunction during peritoneal intoxication. The investigations were carried out on 36 albino rats. I group were included intact animals, II group were included animals that peritoneal exudates reached with products of lipid per oxidation were injected to abdominal cavity and III group were included reached with animals that superoxiddismutase together with products of lipid per oxidation were injected to abdominal cavity.

[Receptor regulation of the platelet activity].

Classification of thrombocyte receptors is given, their functions are discussed, and their endogenous and exogenous ligands are considered as potential targets for antithrombotic drugs.