Publications by authors named "Garyfalia Kempapidou"
Article Synopsis
- - RNA editing is an epitranscriptomic process involving ADAR and APOBEC enzymes that can alter RNA and plays a significant role in various diseases, including autoimmune diseases like multiple sclerosis (MS).
- - The study focused on its impact in a model called experimental autoimmune encephalomyelitis (EAE), which mimics aspects of MS, by analyzing microglia data and testing transgenic mice lacking APOBEC-1.
- - Findings revealed reduced RNA editing events during disease progression in knock-out mice, leading to worse EAE symptoms, suggesting RNA editing regulates mechanisms that may apply to MS and other neurodegenerative disorders.
