Fatal herpes virus type I infection in a newborn.

The authors present a case of environmentally acquired fatal herpes virus type I infection in a newborn after cesarean section and a discussion of the clinical presentation, pathogenesis and diagnosis of herpes simplex type I (HSV-1) at autopsy. Herpes simplex virus, both type I and type II, are well described infectious agents in newborns. Though herpes simplex type II (HSV-2) is commonly associated with fatal neonatal infections, it is important to consider HSV-1 to make the correct diagnosis.

Etiology of pulmonary thromboembolism in the absence of commonly recognized risk factors.

Pulmonary thromboembolism is an often fatal complication of venous thrombosis. Any component or combination of the components composing Virchow's triad (venostasis, hypercoagulability, and endothelial damage) increases the propensity for a thrombophilic state. Hypercoagulable states may be inherited or acquired.

Polydrug fatality involving metaxalone.

A 29-year old female with a history of depression was found dead in a hotel room. The death scene investigation found empty pill bottles and an empty liter bottle of wine. Metaxalone, a centrally acting muscle relaxant, along with citalopram, ethanol, and chlorpheniramine were identified in the postmortem samples and quantitated by gas chromatography-mass spectrometry.