3D Printing of Antibacterial Polymer Devices Based on Nitric Oxide Release from Embedded -Nitrosothiol Crystals.

Controlled release of drugs from medical implants is an effective approach to reducing foreign body reactions and infections. We report here on a one-step 3D printing strategy to create drug-eluting polymer devices with a drug-loaded bulk and a drug-free coating. The spontaneously formed drug-free coating dramatically reduces the surface roughness of the implantable devices and serves as a protective layer to suppress the burst release of drugs.

Optimal oncologic and perioperative outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy are attainable at a community center.

Background: CRS with HIPEC is a complex operation that has shown survival benefit in patients with a variety of primary and metastatic peritoneal surface malignancies. While optimal oncologic and perioperative outcomes have been defined by expert consensus and demonstrated at university-affiliated, academic centers, similar results have never been presented from a non-university-affiliated, community center in the literature to date.

Methods: All cases of CRS with HIPEC performed at a non-university-affiliated, community center were retrospectively reviewed and analyzed.

Is interval appendectomy really needed? A closer look at neoplasm rates in adult patients undergoing interval appendectomy after complicated appendicitis.

Background: The treatment algorithm for appendicitis is evolving, with recent interest in non-operative management. However, the safety of non-operative management for patients with complicated appendicitis has been questioned due to concern for increased risk of occult appendiceal neoplasm in this patient population. Our study aims to determine the rate of neoplasms discovered during interval appendectomy for patients with complicated appendicitis and determine the necessity of interval appendectomy.

Endoscopic transpapillary stenting for the management of acute cholecystitis.

Introduction: Cholecystectomy is the gold standard treatment of acute cholecystitis. Patients who are considered not to be candidates for cholecystectomy are commonly recommended to undergo percutaneous transhepatic gallbladder drainage (PTGBD) tube placement; however, external drainage is undesirable for many patients. Endoscopic transpapillary stent placement (ETSP) has been described as an alternative method for decompression of the gallbladder.

Outcomes following early versus delayed cholecystectomy performed for acute cholangitis.

Background: Early cholecystectomy following an episode of gallstone pancreatitis is data supported, however, there is minimal literature regarding the optimal timing for cholecystectomy following an episode of acute cholangitis. Our study aims to determine the ideal timing for laparoscopic cholecystectomy following an episode of acute cholangitis.

Methods: A retrospective chart review was done on cholecystectomies performed for cholangitis at our institution from 2008 to 2015.

Adaptive systems influence both learning and conscious attention.

The scientific study of animal behavior had its beginnings in two separate scientific traditions. Adaptive explanations, as expanded by ethological studies of natural behavior, emphasized that behavioral traits were guided by innately organized stimulus and response dispositions. Associative explanations, as expanded by conditioning studies, emphasized that behavior was shaped by learned connections formed between stimuli, responses, and motivational outcomes.

ZnS Nanoparticles Sensitize Luminescence of Capping-Ligand-Bound Lanthanide Ions.

2,6-Bis(diethylamide)-4-oxo(3-thiopropane)pyridine (BDP) and 2,6-bis(methyl ester)-4-oxo(3-thiopropane)pyridine (BMP) were synthesized. These compounds chelated Ln ions and sensitized their emission. The 3:1 complexes of BDP displayed efficiencies of 18% and 12% for Eu and Tb, respectively.