A Literature Review of Similarities Between and Among Patients With Autism Spectrum Disorder and Epilepsy.

Autism spectrum disorder (ASD) has been shown to be associated with various other conditions, and most commonly, ASD has been demonstrated to be linked to epilepsy. ASD and epilepsy have been observed to exhibit high rates of comorbidity, even when compared to the co-occurrence of other disorders with similar pathologies. At present, nearly one-half of the individuals diagnosed with ASD also have been diagnosed with comorbid epilepsy.

Critical and Ictal Phases in Simulated EEG Signals on a Small-World Network.

Healthy brain function is marked by neuronal network dynamics at or near the critical phase, which separates regimes of instability and stasis. A failure to remain at this critical point can lead to neurological disorders such as epilepsy, which is associated with pathological synchronization of neuronal oscillations. Using full Hodgkin-Huxley (HH) simulations on a Small-World Network, we are able to generate synthetic electroencephalogram (EEG) signals with intervals corresponding to seizure (ictal) or non-seizure (interictal) states that can occur based on the hyperexcitability of the artificial neurons and the strength and topology of the synaptic connections between them.

Continuity of Care Document (CCD) Enables Delivery of Medication Histories to the Primary Care Clinician.

Introduction: The goal of the Enhanced Medication History (EMH) project is to provide medication histories to ambulatory primary care practices in the Indiana Network for Patient Care.

Methods: Medications were aggregated from three different sources of pharmacy data (Medicaid, SureScripts, and the county health system of Indianapolis). Dispensing events were assembled into the Continuity of Care Document (CCD), and presented to clinicians as RxNorm Clinical Drugs.

A health information technology glossary for novices.

To deliver information to providers across the U.S., the Agency for Healthcare Research and Quality's National Resource Center for Health IT (NRC) created a public domain Web site containing a number of tools and resources.

Facilitating informatics knowledge dissemination: targeted implementation resources for health care providers.

The AHRQ National Resource Center for Health IT (NRC) maintains a public Web site with a large repository of diverse informatics knowledge resources. The NRC recently added a new tool -- the Health IT Bibliography -- to better disseminate key resources to health care organizations. The bibliography filters resources from the NRC's larger online knowledge library, providing quicker access for those who desire to learn more about implementing clinical IT applications.