TETRA observation of gamma-rays at ground level associated with nearby thunderstorms.

[1] Terrestrial gamma-ray flashes (TGFs)-very short, intense bursts of electrons, positrons, and energetic photons originating from terrestrial thunderstorms-have been detected with satellite instruments. TGF and Energetic Thunderstorm Rooftop Array (TETRA), an array of NaI(Tl) scintillators at Louisiana State University, has now been used to detect similar bursts of 50 keV to over 2 MeV gamma-rays at ground level. After 2.

Multiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection.

The 773-residue ectodomain of the herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) has been resistant to the use of mutagenic strategies because the majority of the induced mutations result in defective proteins. As an alternative strategy for the identification of functionally important regions and novel inhibitors of infection, we prepared a library of overlapping peptides homologous to the ectodomain of gB and screened for the ability of the peptides to block infection. Seven of 138 15-mer peptides inhibited infection by more than 50% at a concentration of 100 microM.

Vitreous glutamate concentration and axon loss in monkeys with experimental glaucoma.

Objective: To evaluate vitreous glutamate concentration and axon loss in monkeys with experimental glaucoma.

Methods: We induced unilateral chronic glaucoma by means of laser trabecular destruction in 14 rhesus and 6 cynomolgus monkeys. Intraocular pressure (IOP) was monitored weekly.