Effect of angiotensin receptor blockade on systemic right ventricular function and size: a small, randomized, placebo-controlled study.

Introduction: The effects of angiotensin converting enzyme inhibitor on systemic right ventricular size and function are unknown.

Methods: Prospective, double blind, randomized, placebo-controlled clinical trial of 1-year therapy with Ramipril in adult patients with DTGA status postatrial baffle procedure. Primary endpoints were change in systemic right ventricular ejection fraction (RVEF) and right ventricular size assessed by magnetic resonance imaging (MRI).