Working memory capacity relates to reduced negative emotion in daily life.

Working memory capacity (WMC) refers to the ability to maintain information in short-term memory while attending to the immediate environment, and has been associated with emotional states. Yet, research on the link between WMC and emotion in naturalistic settings is growing and inconsistencies have been observed. In the current study ( = 109), we directly replicated the procedures of a prior experience sampling study (Garrison & Schmeichel, 2022), which found that higher WMC attenuates the relationship between stressful events in daily life and negative affect.

Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in mice.

We identified a novel mouse plasmacytoid dendritic cell (pDC) lineage derived from the common lymphoid progenitors (CLPs) that is dependent on expression of . These CLP-derived pDCs, which we refer to as 'B-pDCs', have a unique gene expression profile that includes hallmark B cell genes, normally not expressed in conventional pDCs. Despite expressing most classical pDC markers such as SIGLEC-H and PDCA1, B-pDCs lack IFN-α secretion, exhibiting a distinct inflammatory profile.

Network state dynamics underpin basal craving in a transdiagnostic population.

Emerging fMRI methods quantifying brain dynamics present an opportunity to capture how fluctuations in brain responses give rise to individual variations in affective and motivation states. Although the experience and regulation of affective states affect psychopathology, their underlying time-varying brain responses remain unclear. Here, we present a novel framework to identify network states matched to an affective experience and examine how the dynamic engagement of these network states contributes to this experience.

Don't Worry About Being You: Relations Between Perceived Authenticity and Mental Health are Due to Self-Esteem and Executive Functioning.

Numerous studies show that perceived authenticity is a reliable predictor of mental health outcomes. To expand on these studies, we examined whether such relations could be due to perceived authenticity's confounding with both self-esteem and executive functioning. A representative sample of US participants ( = 446; = 46.

Smartband-based smoking detection and real-time brief mindfulness intervention: findings from a feasibility clinical trial.

Background: Smartbands can be used to detect cigarette smoking and deliver real time smoking interventions. Brief mindfulness interventions have been found to reduce smoking.

Objective: This single arm feasibility trial used a smartband to detect smoking and deliver brief mindfulness exercises.

Behavioral Precursors of Nicotine Product Use Trajectories Among Youth.

Introduction: Preventing nicotine use among youth is a public health priority. Nicotine use emerges from complex relationships between numerous factors. This project used network analysis to model behavioral precursors of nicotine use (knowledge, attitudes, perceptions, intentions) among youth who had never used nicotine and determine which predicted future trajectories of use across multiple nicotine products.

Smartphone Apps Targeting Youth Tobacco Use Prevention and Cessation: An Assessment of Credibility and Quality.

Purpose Of Review: The goals of this study were to identify smartphone apps targeting youth tobacco use prevention and/or cessation discussed in the academic literature and/or available in the Apple App Store and to review and rate the credibility of the apps. We took a multiphase approach in a non-systematic review that involved conducting parallel literature and App Store searches, screening the returned literature and apps for inclusion, characterizing the studies and apps, and evaluating app quality using a standardized rating scale.

Recent Findings: The negative consequences of youth tobacco use initiation are profound and far-reaching.

Correlation of lesion severity with bacterial changes in Treponeme-Associated Hoof Disease from free-roaming wild elk (Cervus canadensis).

Background: Treponeme-Associated Hoof Disease (TAHD) is a polybacterial, multifactorial disease affecting free-ranging wild elk (Cervus canadensis) in the Pacific Northwest. Previous studies have indicated a bacterial etiology similar to digital dermatitis in livestock, including isolation of Treponema species from lesions. The lesions appear to progress rapidly from ulcerative areas in the interdigital space or along the coronary band to severe, ulcerative, necrotic, proliferative lesions under-running the hoof wall, perforating the sole, and contributing to hoof elongation, deformity, and overgrowth.

Contamination of aquatic ecosystems by persistent organic pollutants (POPs) originating from landfills in Canada and the United States: A rapid scoping review.

Persistent organic pollutants (POPs) are organic chemical substances that threaten human health and the planet's ecosystems due to their toxicity and their ability to remain intact for a long time, wide distribution throughout the environment, and accumulation and magnification in living organisms through the food chain. Discarded products from landfills and dumpsites are potential sources of POPs due to their persistence for several decades and constant release to surrounding environment. POPs in aquatic systems signal input predominantly from landfills, wastewater treatment plants, sewage, and urban runoff, suggesting a research gap to guide policies to address these unabated releases.

Using implementation science to evaluate a population-wide genomic screening program: Findings from the first 20,000 In Our DNA SC participants.

We use the implementation science framework RE-AIM (reach, effectiveness, adoption, implementation, and maintenance) to describe outcomes of In Our DNA SC, a population-wide genomic screening (PWGS) program. In Our DNA SC involves participation through clinical appointments, community events, or at home collection. Participants provide a saliva sample that is sequenced by Helix, and those with a pathogenic variant or likely pathogenic variant for CDC Tier 1 conditions are offered free genetic counseling.

Effects of task switching and emotional stimuli on memory selectivity.

It is not always easy to attend to task-relevant information and ignore task-irrelevant distractions. We investigated the impact of task switching and emotional stimuli on goal-oriented selective attention and subsequent recognition memory. Results from two experiments with different stimulus materials (words and images) found that the memory advantage of task-relevant information over task-irrelevant information (i.

Network state dynamics underpin craving in a transdiagnostic population.

Emerging fMRI brain dynamic methods present a unique opportunity to capture how brain region interactions across time give rise to evolving affective and motivational states. As the unfolding experience and regulation of affective states affect psychopathology and well-being, it is important to elucidate their underlying time-varying brain responses. Here, we developed a novel framework to identify network states specific to an affective state of interest and examine how their instantaneous engagement contributed to its experience.

Smartphone Apps for Smoking Cessation: Systematic Framework for App Review and Analysis.

Background: Cigarette smoking is a leading cause of preventable death, and identifying novel treatment approaches to promote smoking cessation is critical for improving public health. With the rise of digital health and mobile apps, these tools offer potential opportunities to address smoking cessation, yet the functionality of these apps and whether they offer scientifically based support for smoking cessation are unknown.

Objective: The goal of this research was to use the American Psychiatric Association app evaluation model to evaluate the top-returned apps from Android and Apple app store platforms related to smoking cessation and investigate the common app features available for end users.

An exploratory study of topographical signatures within 3D fused deposition modelling using Polylactic Acid (PLA) filament.

This preliminary limited study considers the possibility of the same source identification of consecutively 3D printed components using polymer filament by the examination of deposition artifacts as distinctive macroscopic and microscopic surface characteristics upon the surface of 3D printed objects. Hot-end printer nozzle deposition using polymer filaments can create distinctive surface characteristics upon 3D FDM-printed manufactured objects that can be identified, examined, and compared. Such artifacts can occur as repeatable patterns known as 'deposition striae', 'detachment points', and 'start points' upon the surfaces of an object and on consecutively manufactured components that have used the same 3D Fused Deposition Modelling (FDM) printer hardware.

A Network Investigation of Core Mindfulness Processes.

Objective: Mindfulness has been associated with improved psychological well-being and health, although outcomes from mindfulness-based interventions are mixed. One challenge is a limited understanding about which specific processes are core to mindfulness. Network analysis offers a method to characterize the core processes of mindfulness.

Transdiagnostic Connectome-Based Prediction of Craving.

Objective: Craving is a central construct in the study of motivation and human behavior and is also a clinical symptom of substance and non-substance-related addictive disorders. Thus, craving represents a target for transdiagnostic modeling.

Methods: The authors applied connectome-based predictive modeling (CPM) to functional connectivity data in a large (N=274) transdiagnostic sample of individuals with and without substance use-related conditions, to predict self-reported craving.

Sustainability of Adolescent Screening and Brief Intervention Services in Primary Care After Removal of Implementation Supports.

Objective: Although many health care organizations have sought to increase the integration of substance use services into clinical practice, such practice changes can prove difficult to sustain.

Method: Seven primary care clinics participated in an implementation study of screening and brief intervention (BI) services for adolescent patients (ages 12-17). All sites delivered screening and brief advice (BA) for low-risk use using a uniform protocol.

A Network Analysis of Cigarette Craving.

Introduction: Craving is considered a central process to addictive behavior including cigarette smoking, although the clinical utility of craving relies on how it is defined and measured. Network analysis enables examining the network structure of craving symptoms, identifying the most central symptoms of cigarette craving, and improving our understanding of craving and its measurement.

Aims And Methods: This study used network analysis to identify the central symptoms of self-reported cigarette craving as measured by the Craving Experience Questionnaire, which assesses both craving strength and craving frequency.

Models for Zero-Inflated and Overdispersed Correlated Count Data: An Application to Cigarette Use.

Introduction: Count outcomes in tobacco research are often analyzed with the Poisson distribution. However, they often exhibit features such as overdispersion (variance larger than expected) and zero inflation (extra zeros) that violate model assumptions. Furthermore, longitudinal studies have repeated measures that generate correlated counts.

E-cigarette Marketing Expenditures in the United States From 2016 to 2021: Targeted Media Outlets Geared Toward People Who Are at Increased Risk for Tobacco Use.

Introduction: E-cigarette advertising exposure is linked to e-cigarette initiation and use. Thus, monitoring trends in e-cigarette advertising practices is important to understand e-cigarette use patterns observed over recent years.

Aims And Methods: E-cigarette advertising expenditures (January 2016-July 2021; Numerator Ad Intel) for 154 U.

Lessons Learned from the Pilot Phase of a Population-Wide Genomic Screening Program: Building the Base to Reach a Diverse Cohort of 100,000 Participants.

Background and Objectives: Genomic information is increasingly relevant for disease prevention and risk management at the individual and population levels. Screening healthy adults for Tier 1 conditions of hereditary breast and ovarian cancer, Lynch syndrome, and familial hypercholesterolemia using a population-based approach can help identify the 1−2% of the US population at increased risk of developing diseases associated with these conditions and tailor prevention strategies. Our objective is to report findings from an implementation science study that evaluates multi-level facilitators and barriers to implementation of the In Our DNA SC population-wide genomic screening initiative.

Authentic for Thee But Not for Me: Perceived Authenticity in Self-Control Conflicts.

Is self-control authentic? Across several hypothetical scenarios, participants perceived impulsive actions as more authentic for others (Study 1a) but self-control as more authentic for themselves (Study 1b). Study 2 partially replicated this asymmetry. Study 3 accounted for behavior positivity because self-control was typically the more positive action in the previous studies.

A Molecular Analysis of Memory B Cell and Antibody Responses Against Merozoite Surface Protein 1 in Children and Adults From Uganda.

Memory B cells (MBCs) and plasma antibodies against () merozoite antigens are important components of the protective immune response against malaria. To gain understanding of how responses against develop in these two arms of the humoral immune system, we evaluated MBC and antibody responses against the most abundant merozoite antigen, full-length merozoite surface protein 1 (PfMSP1), in individuals from a region in Uganda with high transmission. Our results showed that PfMSP1-specific B cells in adults with immunological protection against malaria were predominantly IgG classical MBCs, while children with incomplete protection mainly harbored IgM PfMSP1-specific classical MBCs.

Strategies to Promote Health System Strengthening and Global Health Security at the Subnational Level in a World Changed by COVID-19.

Structural weaknesses in national health systems have led to huge variations in responses to COVID-19. This calls for a unified approach to health security and essential health services as public health threats and the expectation for health care systems to provide improved access and services at affordable cost increases.