Publications by authors named "Garrett S Booth"

Article processing charges are increasingly being levied on authors via publication fees to provide open access to readers. These charges may impose challenges to early career physicians seeking to publish research but pathology journal article processing charges have not been investigated to date. We aimed to quantify pathology journal article processing charges and investigate the potential associated factors.

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Alloimmunization to minor red blood cell antigens has been linked to patient morbidity and mortality, especially among people living with sickle cell disease and transfusion-dependent thalassaemia. Prophylactic antigen matching is commonly used to prevent alloimmunization, but the evidence supporting this common practice is very limited. The report by Wolf et al.

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Introduction: Hospital-based transfusion involves hundreds of daily medical decisions. Medical decision-making under uncertainty is susceptible to cognitive biases which can lead to systematic errors of reasoning and suboptimal patient care. Here we review common cognitive biases that may be relevant for transfusion practice.

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Article Synopsis
  • - The neonatal Fc receptor (FcRn) plays a key role in transporting and protecting IgG antibodies, and researchers are exploring the potential of FcRn inhibitors to treat various immune-related diseases.
  • - Studies indicate that FcRn inhibitors can effectively lower total IgG levels without affecting its production or the levels of other antibody types, showing promise as a safer alternative to existing immunosuppressive therapies.
  • - More extensive clinical trials with diverse patient groups are needed to confirm the effectiveness and safety of FcRn inhibitors before they can become standard treatment options for hematologic conditions related to IgG antibodies.
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Article Synopsis
  • Hemolytic disease of the fetus and newborn (HDFN) results from maternal antibodies attacking the fetal red blood cells, but current clinical monitoring practices for it are inconsistent across institutions.
  • A survey of 103 US institutions revealed that while most conduct maternal antibody testing, methods and follow-up practices vary significantly, with only 27% employing cell-free fetal DNA testing to assess fetal risk.
  • The findings indicate a need for standardization in laboratory testing and improved cooperation between blood banks and maternal-fetal medicine services to better manage HDFN risk.
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Background: Trauma remains the leading cause of pediatric mortality in the United States. Although use of massive transfusion protocols (MTPs) in this population is widespread, optimal pediatric resuscitation is not well established. We sought to assess contemporary pediatric MTP practice in the United States.

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Prior studies have suggested that immune thrombotic thrombocytopenic purpura (iTTP) may display seasonal variation; however, methodologic limitations and sample sizes have diminished the ability to perform a rigorous assessment. This 5-year retrospective study assessed the epidemiology of iTTP and determined whether it displays a seasonal pattern. Patients with both initial and relapsed iTTP (defined as a disintegrin and metalloprotease with thrombospondin type motifs 13 activity <10%) from 24 tertiary centers in Australia, Canada, France, Greece, Italy, Spain, and the US were included.

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Article Synopsis
  • A study evaluated apheresis practices in the US through a national survey involving 22 academic medical institutions to identify trends and challenges.
  • The survey revealed that therapeutic plasma exchange (TPE) is the most common procedure, with issues in staffing exacerbated by COVID-19 affecting service delivery.
  • Findings emphasized the importance of apheresis in cellular therapies and the need for innovative staffing solutions in the context of ongoing medical advancements and challenges.
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  • Clinical practice guidelines (CPGs) play a crucial role in shaping medical practices globally, yet the authorship of these guidelines often lacks diversity, particularly underrepresenting women and minority racial and ethnic groups.
  • A study analyzing CPGs from the American Academy of Pediatrics (AAP) between 2010 and 2023 found significant disparities, with women constituting only 39.7% of authors and even lower for women physicians, highlighting an overrepresentation of men in these roles.
  • The findings revealed that all demographics of women and minority men physicians were underrepresented, with a striking absence of Black male authors, emphasizing the need for medical societies to prioritize diversity in authorship for more
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Hematopoietic stem cell transplantation (HSCT) is a cornerstone of modern medical practice, and can only be performed safely and effectively with appropriate transfusion medicine support. Patients undergoing HSCT often develop therapy-related cytopenia, necessitating differing blood product requirements in the pre-, peri-, and post-transplant periods. Moreover, ensuring optimal management for patients alloimmunized to human leukocyte antigens (HLA) and/or red blood cell (RBC) antigens, as well as for patients receiving ABO-incompatible transplants, requires close collaboration with transfusion medicine and blood bank professionals.

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Objectives: The goal of this study was to assess hospital compliance with federal price transparency mandates and barriers to pricing information in Tennessee.

Methods: All hospitals websites were queried for gross, cash, and BlueCross BlueShield of Tennessee prices for 8 high-frequency laboratory tests in 2 Centers for Medicare & Medicaid Services-mandated pricing sources: (1) a machine-readable file of all available services and (2) a consumer-friendly display of 300 shoppable services. Barriers, including click counts, data availability, and intrahospital price discrepancies, were noted.

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Background And Objectives: Promotion in academic medicine requires evidence of the creation and dissemination of scholarly output, primarily through peer-reviewed publications. Studies demonstrate that scholarly activity and impact are lower for women physicians than for men physicians, especially during the early stages of their academic careers. This report reviewed physicians' academic productivity after passing their Blood Banking/Transfusion Medicine (BBTM) subspecialty exam to determine if gender discrepancies exist.

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Objectives: Gender equity studies have shown that women are underrepresented in journal editor in chief positions, which confer major professional opportunities and influence. We sought to systematically investigate editor in chief gender and journal attributes within pathology.

Methods: We constructed a journal data set using the Scimago Journal & Country Rank and Clarivate Journal Citation Reports databases.

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