Psychogenic Hyperphagia: Excessive Eating as Stereotypy in a Patient with Catatonia.

Catatonia is a complex syndrome with unique cognitive, psychomotor, and mood features. Mannerisms and stereotypies are catatonic signs that have been extensively observed and described in the literature, mostly in the context of movements or motor acts. Stereotypies are commonly described as repetitive psychomotor or verbal acts with the abnormality not inherent in the act but in its frequency.

Rethinking Jail Rehabilitation: Evaluating an Intensive Outpatient Program.

The goal of the intensive outpatient program was to provide services to individuals who presented with co-occurring mental health and substance abuse disorders. These services were provided to incarcerated individuals during their involvement with a large Midwestern jail facility in efforts to reduce recidivism. Behavior change is a difficult process for any population, but for those with co-occurring mental health and substance abuse disorders, it is particularly challenging.

Understanding Nutritional Knowledge and Experiences in Families With a Child Newly Diagnosed With Type 1 Diabetes.

Nutrition is an integral part of diabetes management. Caregiver nutritional knowledge has been implicated in glycemic management of youth with type 1 diabetes. This study assessed the nutritional knowledge of parents/caregivers of children newly diagnosed with type 1 diabetes.

"Fearless" Revisited: How This Peer-to-Peer Self-Help Group for Sex Offense Registrants and Their Families Continued to Operate during a Global Pandemic.

Among the challenges of the COVID-19 pandemic, peer-to-peer support groups sought virtual environments to bring individuals together. Building upon previous research of Fearless, a peer-to-peer support group for registered individuals, this study examines how changes in the format from in person to virtual impacted the group's ability to provide social support to members. A snowball sampling technique was used to identify 25 members of Fearless who regularly attended the group's virtual monthly meetings during the COVID social restrictions.

A Case of Constipation and Gastrointestinal Retention of Lisdexamfetamine Dimesylate Capsules in an 11-Year-Old.

Attention deficit hyperactivity disorder (ADHD) has a worldwide prevalence of 5.29% and stimulant medications are considered first-line treatment. Common adverse events with these medications include decreased appetite, increased sleep latency, tics, abdominal pain, and weight loss.

The Americanization of Karen Refugee Youth: Exploring Attitudes Toward and Use of Methamphetamine.

Drug use among refugee populations is a concerning trend in many urban American cities. For instance, Omaha, Nebraska is home to an estimated 7,000 refugees from Myanmar, with at least 75% of those being Karen refugees. The purpose of this paper is to explore methamphetamine use among Karen adolescents in Omaha and to examine whether Karen youth bring their drug use habits with them from refugee camps or if they learn about drugs from their American peers.

The impact of COVID-19-related changes in media consumption on public knowledge: results of a cross-sectional survey of Pennsylvania adults.

Objective: During the COVID-19 pandemic, Americans have increasingly relied on internet versus television news. The extent to which this change in health news consumption practice impacts health knowledge is not known. This study investigates the relationship between most trusted information source and COVID-19 knowledge.

Plasmin-resistant PSD-95 inhibitors resolve effect-modifying drug-drug interactions between alteplase and nerinetide in acute stroke.

Neuroprotection for acute ischemic stroke is achievable with the eicosapeptide nerinetide, an inhibitor of the protein-protein interactions of the synaptic scaffolding protein PSD-95. However, nerinetide is subject to proteolytic cleavage if administered after alteplase, a standard-of-care thrombolytic agent that nullifies nerinetide's beneficial effects. Here, we showed, on the basis of pharmacokinetic data consistent between rats, primates, and humans, that in a rat model of embolic middle cerebral artery occlusion (eMCAO), nerinetide maintained its effectiveness when administered before alteplase.

Knowledge, Perceptions, and Preferred Information Sources Related to COVID-19 Among Healthcare Workers: Results of a Cross Sectional Survey.

Purpose: To compare COVID-19 related knowledge, perceptions, and preferred information sources between healthcare workers and non-healthcare workers.

Design: Cross-sectional survey.

Setting: Web-based.

Electroconvulsive Therapy for Depression in Transgender Patients: Case Series and Literature Review.

There is very limited information regarding the effectiveness of electroconvulsive therapy (ECT) as a treatment for major depressive disorder in transgender patients. This population is also at risk for comorbid conditions, such as posttraumatic stress disorder and substance use that could impact the outcome of ECT. We report our experience with the use of ECT in this population.

Distance running stride-to-stride variability for sagittal plane joint angles.

Recent research indicates that distance running stride-to-stride variability (SSV) is related to performance and injury. Previous studies have primarily focused on stride characteristics (stride length and time). We assessed SSV for sagittal plane joint angles with the primary purpose of testing for significant differences among the lower body joints.

Metabolic testing does not alter distance running lower body sagittal kinematics.

Background: Distance running fitness is commonly assessed using metabolic testing (MT). During MT, the runner must wear a mask that covers the nose and mouth. It is unclear if this increased challenge alters running kinematics and/or stride-to-stride variability (SSV).

High passive-stability diode-laser design for use in atomic-physics experiments.

We present the design and performance characterization of an external-cavity diode-laser system optimized for high stability, low passive spectral linewidth, low cost, and ease of in-house assembly. The main cavity body is machined from a single aluminum block for robustness to temperature changes and mechanical vibrations, and features a stiff and light diffraction-grating arm to suppress low-frequency mechanical resonances. The cavity is vacuum sealed, and a custom-molded silicone external housing further isolates the system from acoustic noise and temperature fluctuations.

Omega-3 fatty acid rich diet prevents diabetic renal disease.

Omega-3 polyunsaturated fatty acids (n-3 PUFA) show beneficial effects in cardiovascular disease, IgA, and diabetic nephropathy; however, the mechanisms underlying these benefits are unknown. The study was performed in male Sprague-Dawley rats randomly divided into four treatment groups: nondiabetic (ND), streptozotocin-induced diabetic (D), diabetic and fed a high n-3 PUFA diet (D+canola), and diabetic and fed a high n-6 (omega-6) PUFA diet (D+corn). Study treatments were carried out for 30 wk.

Imbalance in sex hormone levels exacerbates diabetic renal disease.

Studies suggest that the presence of testosterone exacerbates, whereas the absence of testosterone attenuates, the development of nondiabetic renal disease. However, the effects of the absence of testosterone in diabetic renal disease have not been studied. The study was performed in male Sprague-Dawley nondiabetic, streptozotocin-induced diabetic, and streptozotocin-induced castrated rats (n=10 to 11 per group) for 14 weeks.

Occurrence of exercise dependence in a college-aged population.

Students (n = 257) were evaluated for scope and commitment to physical activity by use of self-reported data that assessed amount of activity per week and the obligatory or pathological nature of their activity patterns. Exhibiting atypical activity patterns, 21.8% of the students in the sample exercised 360 or more minutes per week and demonstrated at least one exercise "dependent" response pattern to queries about obligatory or pathological exercise.

Care management and technology enhance care delivery.

Many health care delivery organizations have experienced a flattening in the rate of their ability to decrease health care costs. Providers--if they are willing to take responsibility for care management and make appropriate investments to support the initiatives--are the logical party to take responsibility for improving care and cost control. Taking responsibility for care management, however, requires the tactical deployment of information technology to enhance care management.

Stimulation of mitochondrial gene expression and proliferation of mitochondria following impairment of cellular energy transfer by inhibition of the phosphocreatine circuit in rat hearts.

Mitochondria proliferate when cellular energy demand increases. However, the pathways leading to enhanced expression of mitochondrial genes are largely unknown. We tested the hypothesis that an altered flux through energy metabolism is the key regulatory event by decreasing mitochondrial energy supply to rat heart cells by creatine depletion.

Detection of specific sugars in dairy process samples using multivariate curve resolution.

Dairy process monitoring by application of multivariate curve resolution using alternating least squares is presented. Alternating least squares was used for resolving Fourier transform infrared spectral data from a dairy batch process in which lactose is enzymatically hydrolyzed to glucose and galactose. It was possible to extract four compounds (fat, lactose, and two other sugar components) from the spectral data obtained from nine process runs.

Near-resonance saturation pulse imaging of the extraocular muscles in thyroid-related ophthalmopathy.

Purpose: We examined the utility of near-resonance saturation pulse imaging (magnetization transfer [MT] and spin lock) in characterizing microstructural changes occurring in the extraocular muscles of patients with thyroid-related ophthalmopathy (TRO).

Methods: Eight healthy volunteers and 10 patients with TRO were imaged using an off-resonance saturation pulse in conjunction with conventional spin-echo T1-weighted imaging at frequency offsets of 500, 1000, 1500, and 2000 Hz from water resonance. The relative contributions of MT and spin-lock excitation to image contrast at each frequency offset were estimated using a computer simulation model.

Acoustic echoplanar scanner noise and pure tone hearing thresholds: the effects of sequence repetition times and acoustic noise rates.

Purpose: Our goal was to determine the effects of acoustic echoplanar scanner noise on pure tone hearing thresholds in normal volunteers and to determine the influence of echoplanar sequence repetition time on threshold effects.

Method: With use of a calibrated audiometer, pure tones ranging from 125 to 8,000 Hz were delivered monaurally to 10 normal-hearing volunteers in a quiet MR scanner suite and in the presence of acoustic scanner noise produced by three separate single shot blipped echoplanar pulse sequences varying only in repetition time (TR = 1,000, 2,000, or 3,000 ms), with all other parameters including the number of slices held constant. The magnitude of noise-induced threshold changes and the slopes of the threshold curves produced by each of the three echoplanar pulse sequences were then analyzed using multiple comparisons and a least significant difference method.

Down-regulation of mitochondrial transcription factor A during spermatogenesis in humans.

Mitochondrial transcription factor A (mtTFA) is a key activator of mitochondrial transcription in mammals. It also has a role in mitochondrial DNA (mtDNA) replication, since transcription generates an RNA primer necessary for initiation of mtDNA replication. In the mouse, testis-specific mtTFA transcripts encode a protein isoform that is imported to the nucleus rather than into mitochondria of spermatocytes and elongating spermatids.

The effect of cations on the hydrolysis of lactose and the transferase reactions catalysed by beta-galactosidase from six strains of lactic acid bacteria.

beta-Galactosidases from Lactobacillus delbruekii subsp. bulgaricus 20056, Lb. casei 20094, Lactococcus lactis subsp.