Synthesis, spectroscopic and toxicity studies of titanocene chelates of isatin-3-thiosemicarbazones.

The reactions of bis(cyclopentadienyl)titanium(IV) dichloride with a new class of thiosemicarbazone (LH(2)), derived by condensing isatin with different N(4)-substituted thiosemicarbazides, have been studied and products of type [Cp(2)Ti(L)] have been isolated. On the basis of various physico-chemical and spectral studies, five coordinate structures have been assigned to these derivatives. Toxicity studies of titanocene complexes at tbur different concentrations have been carried out against snail Lymnaea acuminata.