Radical Resection for Locally Advanced Colon Cancer With Bladder Involvement Treated in a Tertiary Health Care Centre.

Colorectal cancer with involvement of the urinary bladder is infrequent in the nonmetastatic setting. Procedures for advanced colorectal cancers with bladder involvement may include partial or complete bladder resections. Proper therapeutic management principles dictate radical surgery when negative margins can be obtained.

Potential Neurologic Manifestations of COVID-19 Infection in Neonates.

In contrast to adults, neonates and infants with coronavirus disease 2019 (COVID-19) infection have milder symptoms and are less likely to require hospitalization. However, some neonates with COVID-19 can present with significant symptoms. Recent evidence suggests that neurologic manifestations of neonatal COVID-19 infection may be higher than initially thought.

Comprehensive transcriptome analyses of -infected root xylem tissues to decipher genes involved in chickpea wilt resistance.

Unlabelled: Fusarium wilt is the most destructive soil-borne disease that poses a major threat to chickpea production. To comprehensively understand the interaction between chickpea and , the xylem-specific transcriptome analysis of wilt-resistant (WR315) and wilt-susceptible (JG62) genotypes at an early timepoint (4DPI) was investigated. Differential expression analysis showed that 1368 and 348 DEGs responded to pathogen infection in resistant and susceptible genotypes, respectively.

Growth-defense trade-offs and yield loss in plants with engineered cell walls.

As a major component of plant secondary cell walls, lignin provides structural integrity and rigidity, and contributes to primary defense by providing a physical barrier to pathogen ingress. Genetic modification of lignin biosynthesis has been adopted to reduce the recalcitrance of lignified cell walls to improve biofuel production, tree pulping properties and forage digestibility. However, lignin-modification is often, but unpredictably, associated with dwarf phenotypes.

Virtual screening,docking and molecular dynamics simulation of selected phytochemical compounds bound to receptor tyrosine kinases:A correlative anti angiogenic study.

Screening of phytochemicals for their anti angiogenic potential has been a growing area of research in the current decade. The following study proposes virtual screening, drug likeliness and ADME filtering of specific phytochemical based compounds retrieved from "TIP - A Database of Taiwan Indigenous Plants". The study further subjects the filtered phytochemicals for their molecular docking analysis and molecular dynamics simulation studies against the prominent receptor tyrosine kinases EGFR, VEGFR-1 and VEGFR-2 involved in angiogenesis phenomenon.

Dynamical effects of breaking rotational symmetry in counter-rotating Stuart-Landau oscillators.

Stuart-Landau oscillators can be coupled so as to either preserve or destroy the rotational symmetry that the uncoupled system possesses. We examine some of the simplest cases of such couplings for a system of two nonidentical oscillators. When the coupling breaks the rotational invariance, there is a qualitative difference between oscillators wherein the phase velocity has the same sign (termed co-rotation) or opposite signs (termed counter-rotation).

Oscillation death and revival by coupling with damped harmonic oscillator.

Dynamics of nonlinear oscillators augmented with co- and counter-rotating linear damped harmonic oscillator is studied in detail. Depending upon the sense of rotation of augmenting system, the collective dynamics converges to either synchronized periodic behaviour or oscillation death. Multistability is observed when there is a transition from periodic state to oscillation death.

Using complementary approaches to identify trans-domain nuclear gene transfers in the extremophile Galdieria sulphuraria (Rhodophyta).

Identification of horizontal gene transfers (HGTs) has primarily relied on phylogenetic tree based methods, which require a rich sampling of sequenced genomes to ensure a reliable inference. Because the success of phylogenetic approaches depends on the breadth and depth of the database, researchers usually apply stringent filters to detect only the most likely gene transfers in the genomes of interest. One such study focused on a highly conservative estimate of trans-domain gene transfers in the extremophile eukaryote, Galdieria sulphuraria (Galdieri) Merola (Rhodophyta), by applying multiple filters in their phylogenetic pipeline.

Amplitude death phenomena in delay-coupled Hamiltonian systems.

Hamiltonian systems, when coupled via time-delayed interactions, do not remain conservative. In the uncoupled system, the motion can typically be periodic, quasiperiodic, or chaotic. This changes drastically when delay coupling is introduced since now attractors can be created in the phase space.

Dynamical effects of integrative time-delay coupling.

We study coupled dynamical systems wherein the influence of one system on the other is cumulative: coupling signals are integrated over a time interval τ. A major consequence of integrative coupling is that amplitude death occurs over a wider range and in a single region in parameter space. For coupled limit cycle oscillators (the Landau-Stuart model) we obtain an analytic estimate for the boundary of this region while for coupled chaotic Lorenz oscillators numerical results are presented.