Crohn's disease: early detection by gingival biopsy.

A definitive diagnosis of Crohn's disease was made in a 31-year-old female patient who presented with a chief complaint of red, burning gingiva and an itchy palate. The microscopic identification of multinucleated giant cells in the gingival biopsy was suggestive of Crohn's disease. This led to a complete medical work-up including an upper and lower bowel series, which confirmed the diagnosis of Crohn's disease.

Histochemical localization of prostaglandin dehydrogenase activity for PGF-2 alpha in some bovine tissues.

Prostaglandin dehydrogenase activity is histochemically detected in various bovine tissues (kidney, liver, lung, parotid and naso-labial glands) using as substrate prostaglandin F-2 alpha. Kidney, liver and lung showed the highest intensity of the reaction, but parotid and naso-labial glands also displayed enzymatic activity at the level of the ductal cells.

Architecture of sheep haemal nodes.

Sheep haemal nodes are reported to be lymphatic organs within the blood circulation. In this study they were seen to be covered by a capsule of connective tissue, with a hilus in which some blood vessels were detectable. Below the capsule a subcapsular blood sinus and lymphatic nodules were present.

[Partial anterior hypopituitarism caused by toxoplasmosis congenita. Description of a clinical case].

A case of incomplete anterior hypopituitarism due to congenital toxoplasmosis is reported. The rare pituitary involvement in congenital toxoplasmosis and the uncommon remark of associated endocrine symptomatology support this description.

Comparison of multiple views for the evaluation of pulmonary arterial blood flow by Doppler echocardiography.

Forty adult patients underwent Doppler and two-dimensional echocardiographic examination of the pulmonary artery from multiple views to determine the variability in the magnitude of Doppler-determined flow velocity and pulmonary arterial diameter from various echocardiographic windows. Flows were recorded from two or more views in 32 patients (80%). Twelve of these patients (38%) had flow velocities recorded from two or more views that were within 6% of each other.

Angiotensin II inhibition with captopril on plasma ADH, PG synthesis, and renal function in humans.

Using captopril (C), an angiotensin (ANG) I converting-enzyme inhibitor, to increase endogenous prostaglandins (PGs) and to decrease endogenous ANG II synthesis, we studied the relationship between endogenous ANG II, PG, and antidiuretic hormone (ADH) release in seven normal volunteers before (control study) and after inhibition of PG synthesis by a single dose of aspirin (ASA study). In the control study, following the administration of 100 mg of C, there was a significant increase of plasma PGE2, plasma-renin activity (PRA), and urinary PGE2 and 6-keto-PGF1 alpha and a decrease of plasma ADH. Glomerular filtration rate (GFR) and renal plasma flow (RPF) were unaffected by C; urine output, fractional sodium excretion (FENa), and osmolal clearance (Cosmol) increased; and urinary osmolality (Uosmol) decreased significantly after C.

Cytochemical identification of lymphocytes and other mononuclear cells in ovine and bovine hemal nodes.

Cytochemical and immunocytochemical studies were carried out with specific markers for B lymphocytes, dendritic reticulum cells (ATPase, 5'Nase, SIg) and T lymphocytes (ANAE, A.P.) in an attempt to identify the mononuclear cells present in bovine and ovine hemal nodes.

Innervation of the bovine naso-labial glands.

An investigation was carried out on the innervation of bovine naso-labial glands. Histochemical techniques were used to establish the presence and distribution of cholinergic fibres and peptidergic fibres containing VIP and Substance P were revealed by immunohistochemical methods. Parasympathetic nerve fibres were localized around the secretory units and intralobular excretory ducts.

Lectin binding to oral squamous carcinoma.

Ten benign epithelial hyperplasias, ten invasive squamous carcinomas, and one each of verrucous carcinoma and carcinoma in situ of the oral mucosa were examined immunoenzymatically using biotinylated lectins and avidin-biotin-peroxidase complex to localize glycoconjugates in the epithelial cells. All of the lectins intercellularly bind to benign and malignant epithelial cells. Also, lectins bind to the cytoplasm of the basal cells and all layers of carcinoma in situ.

Identification of Langerhans cells in human gingival epithelium.

The purpose of this study was to qualitatively compare three recent techniques of Langerhans cells detection in oral epithelium and to quantitatively compare Langerhans cells in clinically normal and clinically inflamed human gingival biopsies. Eleven subjects were selected who displayed chronic periodontitis and moderate gingival inflammation. A quadrant associated with clinically inflamed tissues was not treated, while the remaining teeth were scaled and root-planed.